“清晰”是什么意思？
该动物不携带突变。就不会发展成这种疾病 并且不会将其传递下去。
猫 肠病性肢端皮炎 (AE)
Acrodermatitis Enteropathica (AE) is a rare, genetic skin condition in cats linked to zinc deficiency. A DNA test can help identify predisposition to this disorder, allowing for early intervention and management. Symptoms of AE include severe skin lesions, hair loss, and lethargy, making timely diagnosis crucial. By understanding your cat's genetic makeup, you can implement dietary changes that may prevent the onset of AE. Regular veterinary check-ups and proper nutrition are essential for maintaining your cat's health. Consider a DNA test for your feline friend to ensure they live a happy, healthy life. Protect your cat from Acrodermatitis Enteropathica today!
缩写 ： AE
分析突变： SLC39A4 c.1057G>C
继承： 常染色体隐性遗传
缩写词
AE
观察频率
临床严重程度
临床分类
皮肤科疾病
分析突变
SLC39A4 c.1057G>C
p.(G353R)
p.(G353R)
继承方式
常染色体隐性遗传 （完全的）
测试总结：
Acrodermatitis Enteropathica (AE) is a rare genetic condition in cats that affects their ability to absorb zinc, leading to severe skin lesions and other health issues. A DNA test can identify specific mutations in the SLC39A4 gene, which are responsible for this disorder. Early detection through genetic testing allows for better management of the condition, ensuring that affected cats receive appropriate care and dietary adjustments. Owners of breeds predisposed to AE, such as certain Siamese and Burmese cats, should consider testing for peace of mind. Understanding this genetic risk helps improve the quality of life for these beloved pets.
可从包装中获取： Basic
我们的包装中已包含此 DNA 测试 Basic — 也是包的一部分 Basic, Standard, Advanced, Complete。
查看 DNA 测试包 →选择最适合您的动物繁殖或健康策略的包装。
Understanding Acrodermatitis Enteropathica (AE) in Cats
Acrodermatitis Enteropathica (AE) is a rare genetic disorder in cats that primarily affects the skin and is associated with zinc deficiency. This condition is characterized by severe dermatitis, especially on the extremities, and can lead to a variety of health complications if not properly managed. AE is often linked to mutations in the gene responsible for zinc absorption, which is critical for numerous biological functions.
Symptoms of Acrodermatitis Enteropathica
The symptoms of AE typically manifest as dermatitis, particularly in areas such as the paws, face, and around the mouth. Affected cats may exhibit redness, swelling, crusting, and scaling of the skin. Additionally, they may experience itching and discomfort, leading to excessive grooming or behavioral changes. Other signs can include diarrhea and weight loss due to malabsorption of nutrients, which can further complicate the health of the cat.
Diagnosis of Acrodermatitis Enteropathica
Diagnosing AE often involves a combination of clinical examination and genetic testing. Veterinarians will assess the cat's symptoms and may perform skin biopsies to rule out other dermatological conditions. Genetic testing can confirm the presence of mutations associated with AE, providing a clear diagnosis and helping guide treatment options.
Treatment Options for Acrodermatitis Enteropathica
The management of AE focuses on addressing the underlying zinc deficiency through dietary modifications and supplementation. Providing a high-quality diet rich in zinc or adding zinc supplements can significantly improve the cat's skin condition and overall health. In some cases, topical treatments may be prescribed to alleviate symptoms, and regular veterinary monitoring is essential to ensure the cat's well-being.
Prognosis and Long-term Management
While AE can be a challenging condition to manage, many cats can lead healthy lives with appropriate care. Continuous monitoring of zinc levels and regular veterinary check-ups are crucial to adjust treatment plans as needed. Owners should be vigilant in observing their cat's condition and report any changes to their veterinarian for timely intervention.
结论
Acrodermatitis Enteropathica is a serious condition that requires prompt diagnosis and management. Understanding the implications of this disorder, along with proper treatment strategies, can help ensure that affected cats receive the care they need to thrive. With the right approach, the prognosis for cats with AE can be positive, allowing them to live comfortably and healthily.
被认可参加测试的品种： 肠病性肢端皮炎 (AE)
- Turkish Van
🧬 Interpretation of genotypes AE
基因型
地位
🟡 N/N
非承运人 - 无风险
🟡 N/AE
承运人 - 无风险
❌ AE/AE
受影响 - 面临风险
常见问题解答：理解解释
“航母”是认真的吗？
不会。该动物通常是健康的，但可以将突变传播给它的 后代。
如果动物“受到影响”怎么办？
它携带两个突变的副本。预计临床症状取决于 这种疾病。它不应该被培育。
为什么男性/女性之间存在差异？
有些疾病与性别相关，因此其表现因性别而异 动物的性别。
预测后代
N/N （%e9%9d%9e%e6%89%bf%e8%bf%90%e4%ba%ba）
N/AE （载体）
AE/AE （做作的）
DNA 测试常见问题解答
这个 DNA 测试检测到什么？
This DNA test detects the mutation associated with Acrodermatitis Enteropathica (AE) in order to identify clear, carrier, or at-risk animals.
为什么要测试繁殖动物？
DNA 测试有助于饲养员计划更安全的交配并降低将突变传播给后代的风险。
这个测试的继承模式是什么？
该测试报告的遗传模式是常染色体隐性遗传。
此测试分析哪种突变？
This test analyses the mutation SLC39A4 c.1057G>C.
携带动物是否必然受到影响？
未必。解释取决于遗传模式和产生的基因型。
参考
Kiener Sarah, Cikota Robert, Welle Monika, Jagannathan Vidhya, Åhman Susanne, Leeb Tosso. A Missense Variant in SLC39A4 in a Litter of Turkish Van Cats with Acrodermatitis Enteropathica. Genes (Basel). 2021 Aug 25;12(9):1309. doi: 10.3390/genes12091309.