「清晰」係咩意思？
呢隻動物唔會攜帶呢個突變。佢唔會發病 同埋唔會傳落去。
貓 腸病性肢端皮炎（ AE ）
Acrodermatitis Enteropathica (AE) is a rare, genetic skin condition in cats linked to zinc deficiency. A DNA test can help identify predisposition to this disorder, allowing for early intervention and management. Symptoms of AE include severe skin lesions, hair loss, and lethargy, making timely diagnosis crucial. By understanding your cat's genetic makeup, you can implement dietary changes that may prevent the onset of AE. Regular veterinary check-ups and proper nutrition are essential for maintaining your cat's health. Consider a DNA test for your feline friend to ensure they live a happy, healthy life. Protect your cat from Acrodermatitis Enteropathica today!
縮寫： AE
分析咗嘅突變： SLC39A4 c.1057G>C
遺產 ： 常染色體隱性
首字母縮寫
AE
觀察到嘅頻率
臨床嚴重性
臨床分類
皮膚病
分析咗嘅突變
SLC39A4 c.1057G>C
p.(G353R)
p.(G353R)
繼承方式
常染色體隱性 （完成）
測試摘要：
Acrodermatitis Enteropathica (AE) is a rare genetic condition in cats that affects their ability to absorb zinc, leading to severe skin lesions and other health issues. A DNA test can identify specific mutations in the SLC39A4 gene, which are responsible for this disorder. Early detection through genetic testing allows for better management of the condition, ensuring that affected cats receive appropriate care and dietary adjustments. Owners of breeds predisposed to AE, such as certain Siamese and Burmese cats, should consider testing for peace of mind. Understanding this genetic risk helps improve the quality of life for these beloved pets.
喺包裝入面有得買： Basic
呢個 DNA 測試由我哋嘅包裝開始包括喺入面 Basic — 而且亦都係包嘅一部分 Basic, Standard, Advanced, Complete。
查看 DNA 檢測包 →揀最適合你嘅動物嘅繁殖或者健康策略嘅群體。
Understanding Acrodermatitis Enteropathica (AE) in Cats
Acrodermatitis Enteropathica (AE) is a rare genetic disorder in cats that primarily affects the skin and is associated with zinc deficiency. This condition is characterized by severe dermatitis, especially on the extremities, and can lead to a variety of health complications if not properly managed. AE is often linked to mutations in the gene responsible for zinc absorption, which is critical for numerous biological functions.
Symptoms of Acrodermatitis Enteropathica
The symptoms of AE typically manifest as dermatitis, particularly in areas such as the paws, face, and around the mouth. Affected cats may exhibit redness, swelling, crusting, and scaling of the skin. Additionally, they may experience itching and discomfort, leading to excessive grooming or behavioral changes. Other signs can include diarrhea and weight loss due to malabsorption of nutrients, which can further complicate the health of the cat.
Diagnosis of Acrodermatitis Enteropathica
Diagnosing AE often involves a combination of clinical examination and genetic testing. Veterinarians will assess the cat's symptoms and may perform skin biopsies to rule out other dermatological conditions. Genetic testing can confirm the presence of mutations associated with AE, providing a clear diagnosis and helping guide treatment options.
Treatment Options for Acrodermatitis Enteropathica
The management of AE focuses on addressing the underlying zinc deficiency through dietary modifications and supplementation. Providing a high-quality diet rich in zinc or adding zinc supplements can significantly improve the cat's skin condition and overall health. In some cases, topical treatments may be prescribed to alleviate symptoms, and regular veterinary monitoring is essential to ensure the cat's well-being.
Prognosis and Long-term Management
While AE can be a challenging condition to manage, many cats can lead healthy lives with appropriate care. Continuous monitoring of zinc levels and regular veterinary check-ups are crucial to adjust treatment plans as needed. Owners should be vigilant in observing their cat's condition and report any changes to their veterinarian for timely intervention.
結論
Acrodermatitis Enteropathica is a serious condition that requires prompt diagnosis and management. Understanding the implications of this disorder, along with proper treatment strategies, can help ensure that affected cats receive the care they need to thrive. With the right approach, the prognosis for cats with AE can be positive, allowing them to live comfortably and healthily.
測試認可嘅品種： 腸病性肢端皮炎（ AE ）
- Turkish Van
🧬 Interpretation of genotypes AE
基因型
地位
🟡 N/N
非航空公司 - 冇風險
🟡 N/AE
航空公司 - 冇風險
❌ AE/AE
受影響 - 有風險
常見問題：理解解釋
「承載者」係咪認真？
唔係。隻動物一般都係健康嘅，但係可以將突變傳染畀佢 後代。
如果一隻動物係「受影響」嘅話點算好？
佢有兩個突變嘅副本。預計會有臨床症狀，視乎情況而定 個病。唔應該繁殖。
點解男 / 女有分別？
有啲疾病係同性別有關，所以佢哋嘅表現會因疾病而異 動物嘅性別。
預測後代
N/N （%e9%9d%9e%e6%b5%81%e5%8b%95%e7%b6%b2%e7%b5%a1%e4%be%9b%e6%87%89%e5%95%86）
N/AE （航空公司）
AE/AE （受影響）
DNA 測試常見問題
呢個 DNA 測試可以檢測到啲咩？
This DNA test detects the mutation associated with Acrodermatitis Enteropathica (AE) in order to identify clear, carrier, or at-risk animals.
點解要測試一隻繁殖動物？
DNA 檢測有助養殖者計劃更安全嘅交配，同埋減低將突變傳播畀後代嘅風險。
呢個測試嘅繼承模式係點？
呢個測試報告嘅遺傳模式係常染色體隱性。
呢個測試會分析邊個突變？
This test analyses the mutation SLC39A4 c.1057G>C.
載體動物係咪一定會受到影響？
唔一定。解釋取決於遺傳模式同所產生嘅基因型。
參考文獻
Kiener Sarah, Cikota Robert, Welle Monika, Jagannathan Vidhya, Åhman Susanne, Leeb Tosso. A Missense Variant in SLC39A4 in a Litter of Turkish Van Cats with Acrodermatitis Enteropathica. Genes (Basel). 2021 Aug 25;12(9):1309. doi: 10.3390/genes12091309.