「清晰」是什麼意思？
該動物不攜帶突變。就不會發展成這種疾病 並且不會傳遞下去。
貓 Acrodermatitis Enteropathica (AE)
Acrodermatitis Enteropathica (AE) is a rare, genetic skin condition in cats linked to zinc deficiency. A DNA test can help identify predisposition to this disorder, allowing for early intervention and management. Symptoms of AE include severe skin lesions, hair loss, and lethargy, making timely diagnosis crucial. By understanding your cat's genetic makeup, you can implement dietary changes that may prevent the onset of AE. Regular veterinary check-ups and proper nutrition are essential for maintaining your cat's health. Consider a DNA test for your feline friend to ensure they live a happy, healthy life. Protect your cat from Acrodermatitis Enteropathica today!
縮寫 ： AE
分析突變： SLC39A4 c.1057G>C
繼承： 體染色體隱性遺傳
縮寫詞
AE
觀察頻率
臨床嚴重程度
臨床分類
皮膚科疾病
分析突變
SLC39A4 c.1057G>C
p.(G353R)
p.(G353R)
繼承方式
體染色體隱性遺傳 （完全的）
測試總結：
Acrodermatitis Enteropathica (AE) is a rare genetic condition in cats that affects their ability to absorb zinc, leading to severe skin lesions and other health issues. A DNA test can identify specific mutations in the SLC39A4 gene, which are responsible for this disorder. Early detection through genetic testing allows for better management of the condition, ensuring that affected cats receive appropriate care and dietary adjustments. Owners of breeds predisposed to AE, such as certain Siamese and Burmese cats, should consider testing for peace of mind. Understanding this genetic risk helps improve the quality of life for these beloved pets.
可從包裝中取得： Basic
我們的包裝中已包含此 DNA 測試 Basic — 也是包包的一部分 Basic, Standard, Advanced, Complete。
查看 DNA 測試包 →選擇最適合您的動物繁殖或健康策略的包裝。
Understanding Acrodermatitis Enteropathica (AE) in Cats
Acrodermatitis Enteropathica (AE) is a rare genetic disorder in cats that primarily affects the skin and is associated with zinc deficiency. This condition is characterized by severe dermatitis, especially on the extremities, and can lead to a variety of health complications if not properly managed. AE is often linked to mutations in the gene responsible for zinc absorption, which is critical for numerous biological functions.
Symptoms of Acrodermatitis Enteropathica
The symptoms of AE typically manifest as dermatitis, particularly in areas such as the paws, face, and around the mouth. Affected cats may exhibit redness, swelling, crusting, and scaling of the skin. Additionally, they may experience itching and discomfort, leading to excessive grooming or behavioral changes. Other signs can include diarrhea and weight loss due to malabsorption of nutrients, which can further complicate the health of the cat.
Diagnosis of Acrodermatitis Enteropathica
Diagnosing AE often involves a combination of clinical examination and genetic testing. Veterinarians will assess the cat's symptoms and may perform skin biopsies to rule out other dermatological conditions. Genetic testing can confirm the presence of mutations associated with AE, providing a clear diagnosis and helping guide treatment options.
Treatment Options for Acrodermatitis Enteropathica
The management of AE focuses on addressing the underlying zinc deficiency through dietary modifications and supplementation. Providing a high-quality diet rich in zinc or adding zinc supplements can significantly improve the cat's skin condition and overall health. In some cases, topical treatments may be prescribed to alleviate symptoms, and regular veterinary monitoring is essential to ensure the cat's well-being.
Prognosis and Long-term Management
While AE can be a challenging condition to manage, many cats can lead healthy lives with appropriate care. Continuous monitoring of zinc levels and regular veterinary check-ups are crucial to adjust treatment plans as needed. Owners should be vigilant in observing their cat's condition and report any changes to their veterinarian for timely intervention.
結論
Acrodermatitis Enteropathica is a serious condition that requires prompt diagnosis and management. Understanding the implications of this disorder, along with proper treatment strategies, can help ensure that affected cats receive the care they need to thrive. With the right approach, the prognosis for cats with AE can be positive, allowing them to live comfortably and healthily.
被認可參加測試的品種： Acrodermatitis Enteropathica (AE)
- Turkish Van
🧬 Interpretation of genotypes AE
基因型
地位
🟡 N/N
非承運人 - 無風險
🟡 N/AE
承運人 - 無風險
❌ AE/AE
受影響 - 面臨風險
常見問題：理解解釋
「航母」是認真的嗎？
不會。該動物通常是健康的，但可以將突變傳播給它的 後代。
如果動物「受到影響」怎麼辦？
它攜帶兩個突變的副本。預計臨床症狀取決於 這種疾病。它不應該被培育。
為什麼男性/女性之間會有差異？
有些疾病與性別有關，因此其表現因性別而異 動物的性別。
預測後代
N/N （%e9%9d%9e%e6%89%bf%e9%81%8b%e4%ba%ba）
N/AE （載體）
AE/AE （做作的）
DNA 測試常見問題解答
這個 DNA 測試檢測到什麼？
This DNA test detects the mutation associated with Acrodermatitis Enteropathica (AE) in order to identify clear, carrier, or at-risk animals.
為什麼要測試繁殖動物？
DNA 測試有助於飼養員計劃更安全的交配並降低將突變傳播給後代的風險。
這個測試的繼承模式是什麼？
此測試報告的遺傳模式是體染色體隱性遺傳。
此測試分析哪一種突變？
This test analyses the mutation SLC39A4 c.1057G>C.
攜帶動物是否必然受到影響？
未必。解釋取決於遺傳模式和產生的基因型。
參考
Kiener Sarah, Cikota Robert, Welle Monika, Jagannathan Vidhya, Åhman Susanne, Leeb Tosso. A Missense Variant in SLC39A4 in a Litter of Turkish Van Cats with Acrodermatitis Enteropathica. Genes (Basel). 2021 Aug 25;12(9):1309. doi: 10.3390/genes12091309.