狗 Screw Tail (ST)

依品種或臨床分類過濾 DNA 測試

The Screw Tail (ST) DNA test in dogs is essential for identifying genetic markers linked to screw tail deformities. This hereditary condition affects the shape of a dog’s tail, often seen in breeds like Bulldogs and Pugs. By using the Screw Tail DNA test, breeders and owners can make informed decisions to reduce the risk of passing this trait to future generations. Early detection through genetic testing helps improve breeding programs and promotes healthier puppies. The test is quick, accurate, and non-invasive, requiring only a simple cheek swab. Understanding your dog’s genetic makeup with the Screw Tail DNA test supports responsible breeding and overall canine health. Stay proactive and protect your dog’s well-being with this vital genetic screening.

縮寫 ： ST

分析突變： DVL2 c.2051del

繼承： 體染色體顯性遺傳

可從包裝中取得： Standard

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選擇最適合您的動物繁殖或健康策略的包裝。

Understanding Screw Tail (ST) in Dogs

Screw Tail (ST) is a congenital condition characterized by an abnormal curvature of the tail in dogs. This condition can manifest in various degrees, ranging from mild kinks to severe twists that may lead to discomfort or health complications. The genetic basis of Screw Tail has been a focal point of research, with studies indicating that it can be inherited in certain breeds. Understanding this condition is essential for breeders and dog owners alike, as it can impact the quality of life of affected dogs.

Symptoms and Physical Characteristics

The primary symptom of Screw Tail is the noticeable deformity of the tail. In affected dogs, the tail may appear short or twisted, and its position may be lower than that of a typical tail. In some cases, the abnormality can lead to skin irritation or infections due to the tail’s inability to maintain proper hygiene. Additionally, dogs with severe Screw Tail might exhibit signs of pain or discomfort, particularly when the tail is touched or manipulated.

Potential Health Complications

While some dogs with Screw Tail may lead normal lives, others can face various health complications. One of the most common issues is chronic skin irritation, as the abnormal tail structure can trap moisture and debris. This can lead to frequent infections and require ongoing veterinary care. Furthermore, in severe cases, the abnormal tail may interfere with the dog’s ability to communicate through body language, potentially leading to behavioral issues.

Genetic Testing for Screw Tail

DNA testing for Screw Tail is an important tool for breeders and pet owners. By identifying the presence of genes associated with this condition, breeders can make informed decisions about mating pairs to minimize the risk of producing puppies with Screw Tail. Genetic testing can provide valuable insights into the likelihood of this condition appearing in future generations, thereby promoting healthier breeding practices.

管理和治療方案

Management of Screw Tail typically involves regular veterinary check-ups to monitor for any skin issues or infections. In cases where the tail deformity leads to significant discomfort or health problems, surgical intervention may be considered. Tail amputation is a possibility in severe cases, although it is generally viewed as a last resort. Maintaining good hygiene practices and providing proper care can help mitigate some of the complications associated with this condition.

結論

Screw Tail is a condition that can affect the quality of life for some dogs, depending on the severity of the deformity. Understanding the implications of this genetic disorder is crucial for responsible breeding and ownership. With advancements in genetic testing, there is hope for reducing the prevalence of this condition and ensuring a better quality of life for affected dogs.

被認可參加測試的品種： Screw Tail (ST)

• American Bulldog
• American Bully
• American Pit Bull Terrier
• American Staffordshire Terrier
• Boston Terrier
• Bull Terrier
• Bulldog
• Bullmastiff
• French Bulldog
• Staffordshire Bull Terrier

🧬 Interpretation of genotypes ST

❓ 了解有關基因型解釋的更多信息

常見問題：理解解釋

「清晰」是什麼意思？

該動物不攜帶突變。就不會發展成這種疾病 並且不會傳遞下去。

「航母」是認真的嗎？

不會。該動物通常是健康的，但可以將突變傳播給它的 後代。

如果動物「受到影響」怎麼辦？

它攜帶兩個突變的副本。預計臨床症狀取決於 這種疾病。它不應該被培育。

為什麼男性/女性之間會有差異？

有些疾病與性別有關，因此其表現因性別而異 動物的性別。

預測後代

DNA 測試常見問題解答

這個 DNA 測試檢測到什麼？

This DNA test detects the mutation associated with Screw Tail (ST) in order to identify clear, carrier, or at-risk animals.

為什麼要測試繁殖動物？

DNA 測試有助於飼養員計劃更安全的交配並降低將突變傳播給後代的風險。

這個測試的​​繼承模式是什麼？

此測試報告的遺傳模式是體染色體顯性遺傳。

此測試分析哪一種突變？

This test analyses the mutation DVL2 c.2051del.

攜帶動物是否必然受到影響？

未必。解釋取決於遺傳模式和產生的基因型。

參考

Mansour Tamer A, Lucot Katherine, Konopelski Sara E, Dickinson Peter J, Sturges Beverly K, Vernau Karen L, Choi Shannon, Stern Joshua A, Thomasy Sara M, Döring Sophie, Verstraete Frank J M, Johnson Eric G, York Daniel, Rebhun Robert B, Ho HsinYi Henry, Brown C Titus, Bannasch Danika L. Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds. PLoS Genet. 2018 Dec 6;14(12):e1007850. doi: 10.1371/journal.pgen.1007850. eCollection 2018 Dec.