O que significa “Limpar”?
O animal não carrega a mutação. Não desenvolverá a doença e não vai passar adiante.
Cachorro Cauda do Parafuso (ST)
The Screw Tail (ST) DNA test in dogs is essential for identifying genetic markers linked to screw tail deformities. This hereditary condition affects the shape of a dog’s tail, often seen in breeds like Bulldogs and Pugs. By using the Screw Tail DNA test, breeders and owners can make informed decisions to reduce the risk of passing this trait to future generations. Early detection through genetic testing helps improve breeding programs and promotes healthier puppies. The test is quick, accurate, and non-invasive, requiring only a simple cheek swab. Understanding your dog’s genetic makeup with the Screw Tail DNA test supports responsible breeding and overall canine health. Stay proactive and protect your dog’s well-being with this vital genetic screening.
Abreviatura: ST
Mutação analisada: DVL2 c.2051del
Herança: Autossômico Dominante
Acrônimo
ST
Frequência observada
Classificação clínica
Características Relacionadas à Cauda
Mutação analisada
DVL2 c.2051del
p.(P684Lfs*26)
p.(P684Lfs*26)
Modo de herança
Autossômico Dominante
Resumo do teste:
The Screw Tail (ST) DNA test in dogs identifies a genetic mutation responsible for the distinctive twisted tail shape seen in certain breeds. This test helps breeders avoid mating two carriers, reducing the risk of puppies inheriting the deformity. It is especially important in breeds like Bulldogs and Boston Terriers, where the screw tail is common. By using the ST test, breeders can promote healthier litters and maintain breed standards. Overall, the test supports responsible breeding and canine health management.
Disponível no pacote: Standard
Este teste de DNA está incluído a partir do nosso pacote Standard - e também faz parte dos packs Standard, Advanced, Complete.
Ver pacotes de teste de DNA →Escolha o pack que melhor se adapta à sua estratégia de criação ou saúde dos seus animais.
Understanding Screw Tail (ST) in Dogs
Screw Tail (ST) is a congenital condition characterized by an abnormal curvature of the tail in dogs. This condition can manifest in various degrees, ranging from mild kinks to severe twists that may lead to discomfort or health complications. The genetic basis of Screw Tail has been a focal point of research, with studies indicating that it can be inherited in certain breeds. Understanding this condition is essential for breeders and dog owners alike, as it can impact the quality of life of affected dogs.
Symptoms and Physical Characteristics
The primary symptom of Screw Tail is the noticeable deformity of the tail. In affected dogs, the tail may appear short or twisted, and its position may be lower than that of a typical tail. In some cases, the abnormality can lead to skin irritation or infections due to the tail’s inability to maintain proper hygiene. Additionally, dogs with severe Screw Tail might exhibit signs of pain or discomfort, particularly when the tail is touched or manipulated.
Potential Health Complications
While some dogs with Screw Tail may lead normal lives, others can face various health complications. One of the most common issues is chronic skin irritation, as the abnormal tail structure can trap moisture and debris. This can lead to frequent infections and require ongoing veterinary care. Furthermore, in severe cases, the abnormal tail may interfere with the dog’s ability to communicate through body language, potentially leading to behavioral issues.
Genetic Testing for Screw Tail
DNA testing for Screw Tail is an important tool for breeders and pet owners. By identifying the presence of genes associated with this condition, breeders can make informed decisions about mating pairs to minimize the risk of producing puppies with Screw Tail. Genetic testing can provide valuable insights into the likelihood of this condition appearing in future generations, thereby promoting healthier breeding practices.
Opções de manejo e tratamento
Management of Screw Tail typically involves regular veterinary check-ups to monitor for any skin issues or infections. In cases where the tail deformity leads to significant discomfort or health problems, surgical intervention may be considered. Tail amputation is a possibility in severe cases, although it is generally viewed as a last resort. Maintaining good hygiene practices and providing proper care can help mitigate some of the complications associated with this condition.
Conclusão
Screw Tail is a condition that can affect the quality of life for some dogs, depending on the severity of the deformity. Understanding the implications of this genetic disorder is crucial for responsible breeding and ownership. With advancements in genetic testing, there is hope for reducing the prevalence of this condition and ensuring a better quality of life for affected dogs.
Raça reconhecida para o teste: Cauda do Parafuso (ST)
- American Bulldog
- American Bully
- American Pit Bull Terrier
- American Staffordshire Terrier
- Boston Terrier
- Bull Terrier
- Bulldog
- Bullmastiff
- French Bulldog
- Staffordshire Bull Terrier
🧬 Interpretation of genotypes ST
Genótipo
Status
🟡 N/N
Não portador – Sem efeito
🟡 N/ST
Carrier - Screw Tail
❌ ST/ST
Affected - Screw Tail
FAQ: entendendo a interpretação
Um “transportador” é sério?
Não. O animal é geralmente saudável, mas pode transmitir a mutação ao seu descendência.
E se um animal for “afetado”?
Ele carrega duas cópias mutadas. Os sinais clínicos são esperados dependendo a doença. Não deveria ser criado.
Por que existem diferenças entre homem/mulher?
Algumas doenças estão ligadas ao sexo, pelo que a sua expressão varia dependendo do sexo do animal.
Prever descendência
N/N (nao-portador)
N/ST (Operadora)
ST/ST (Afetado)
Perguntas frequentes sobre testes de DNA
O que este teste de DNA detecta?
This DNA test detects the mutation associated with Screw Tail (ST) in order to identify clear, carrier, or at-risk animals.
Por que testar um animal reprodutor?
Os testes de DNA ajudam os criadores a planejar acasalamentos mais seguros e a reduzir o risco de transmissão da mutação aos descendentes.
Qual é o modo de herança deste teste?
O modo de herança relatado para este teste é Autossômico Dominante.
Qual mutação é analisada neste teste?
This test analyses the mutation DVL2 c.2051del.
Um animal portador é necessariamente afetado?
Não necessariamente. A interpretação depende do padrão de herança e do genótipo resultante.
Referências
Mansour Tamer A, Lucot Katherine, Konopelski Sara E, Dickinson Peter J, Sturges Beverly K, Vernau Karen L, Choi Shannon, Stern Joshua A, Thomasy Sara M, Döring Sophie, Verstraete Frank J M, Johnson Eric G, York Daniel, Rebhun Robert B, Ho HsinYi Henry, Brown C Titus, Bannasch Danika L. Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds. PLoS Genet. 2018 Dec 6;14(12):e1007850. doi: 10.1371/journal.pgen.1007850. eCollection 2018 Dec.