Hva betyr "Tøm"?
Dyret bærer ikke mutasjonen. Det vil ikke utvikle sykdommen og vil ikke gi det videre.
Hund Screw Tail (ST)
The Screw Tail (ST) DNA test in dogs is essential for identifying genetic markers linked to screw tail deformities. This hereditary condition affects the shape of a dog’s tail, often seen in breeds like Bulldogs and Pugs. By using the Screw Tail DNA test, breeders and owners can make informed decisions to reduce the risk of passing this trait to future generations. Early detection through genetic testing helps improve breeding programs and promotes healthier puppies. The test is quick, accurate, and non-invasive, requiring only a simple cheek swab. Understanding your dog’s genetic makeup with the Screw Tail DNA test supports responsible breeding and overall canine health. Stay proactive and protect your dog’s well-being with this vital genetic screening.
Forkortelse: ST
Analysert mutasjon: DVL2 c.2051del
Arv: Autosomal Dominant
Akronym
ST
Observert frekvens
Klinisk klassifisering
Halerelaterte egenskaper
Analysert mutasjon
DVL2 c.2051del
p.(P684Lfs*26)
p.(P684Lfs*26)
Metode for arv
Autosomal Dominant
Testsammendrag:
The Screw Tail (ST) DNA test in dogs identifies a genetic mutation responsible for the distinctive twisted tail shape seen in certain breeds. This test helps breeders avoid mating two carriers, reducing the risk of puppies inheriting the deformity. It is especially important in breeds like Bulldogs and Boston Terriers, where the screw tail is common. By using the ST test, breeders can promote healthier litters and maintain breed standards. Overall, the test supports responsible breeding and canine health management.
Tilgjengelig fra pakken: Standard
Denne DNA-testen er inkludert fra pakken vår Standard — og er også en del av pakkene Standard, Advanced, Complete.
Se DNA-testpakker →Velg pakken som passer best til din avl eller helsestrategi for dyrene dine.
Understanding Screw Tail (ST) in Dogs
Screw Tail (ST) is a congenital condition characterized by an abnormal curvature of the tail in dogs. This condition can manifest in various degrees, ranging from mild kinks to severe twists that may lead to discomfort or health complications. The genetic basis of Screw Tail has been a focal point of research, with studies indicating that it can be inherited in certain breeds. Understanding this condition is essential for breeders and dog owners alike, as it can impact the quality of life of affected dogs.
Symptoms and Physical Characteristics
The primary symptom of Screw Tail is the noticeable deformity of the tail. In affected dogs, the tail may appear short or twisted, and its position may be lower than that of a typical tail. In some cases, the abnormality can lead to skin irritation or infections due to the tail’s inability to maintain proper hygiene. Additionally, dogs with severe Screw Tail might exhibit signs of pain or discomfort, particularly when the tail is touched or manipulated.
Potential Health Complications
While some dogs with Screw Tail may lead normal lives, others can face various health complications. One of the most common issues is chronic skin irritation, as the abnormal tail structure can trap moisture and debris. This can lead to frequent infections and require ongoing veterinary care. Furthermore, in severe cases, the abnormal tail may interfere with the dog’s ability to communicate through body language, potentially leading to behavioral issues.
Genetic Testing for Screw Tail
DNA testing for Screw Tail is an important tool for breeders and pet owners. By identifying the presence of genes associated with this condition, breeders can make informed decisions about mating pairs to minimize the risk of producing puppies with Screw Tail. Genetic testing can provide valuable insights into the likelihood of this condition appearing in future generations, thereby promoting healthier breeding practices.
Administrasjons- og behandlingsalternativer
Management of Screw Tail typically involves regular veterinary check-ups to monitor for any skin issues or infections. In cases where the tail deformity leads to significant discomfort or health problems, surgical intervention may be considered. Tail amputation is a possibility in severe cases, although it is generally viewed as a last resort. Maintaining good hygiene practices and providing proper care can help mitigate some of the complications associated with this condition.
Konklusjon
Screw Tail is a condition that can affect the quality of life for some dogs, depending on the severity of the deformity. Understanding the implications of this genetic disorder is crucial for responsible breeding and ownership. With advancements in genetic testing, there is hope for reducing the prevalence of this condition and ensuring a better quality of life for affected dogs.
Rase anerkjent for testen: Screw Tail (ST)
- American Bulldog
- American Bully
- American Pit Bull Terrier
- American Staffordshire Terrier
- Boston Terrier
- Bull Terrier
- Bulldog
- Bullmastiff
- French Bulldog
- Staffordshire Bull Terrier
🧬 Interpretation of genotypes ST
Genotype
Status
🟡 N/N
Ikke-bærer - Ingen effekt
🟡 N/ST
Carrier - Screw Tail
❌ ST/ST
Affected - Screw Tail
FAQ: forstå tolkningen
Er en "Carrier" seriøs?
Nei. Dyret er generelt sunt, men kan overføre mutasjonen til dens avkom.
Hva om et dyr er "påvirket"?
Den har to muterte kopier. Kliniske tegn forventes avhengig av sykdommen. Det skal ikke avles.
Hvorfor er det forskjeller mellom mann og kvinne?
Noen sykdommer er kjønnsbundne, så uttrykket deres varierer avhengig av dyrs kjønn.
Forutsi avkom
N/N (ikke-transportor)
N/ST (Transportør)
ST/ST (Berørt)
Vanlige spørsmål om DNA-test
Hva oppdager denne DNA-testen?
This DNA test detects the mutation associated with Screw Tail (ST) in order to identify clear, carrier, or at-risk animals.
Hvorfor teste et avlsdyr?
DNA-testing hjelper oppdrettere med å planlegge sikrere parringer og redusere risikoen for å overføre mutasjonen til avkom.
Hva er arvemodusen for denne testen?
Arvemodusen som er rapportert for denne testen er Autosomal Dominant.
Hvilken mutasjon analyseres i denne testen?
This test analyses the mutation DVL2 c.2051del.
Er et bærerdyr nødvendigvis påvirket?
Ikke nødvendigvis. Tolkning avhenger av arvemønsteret og den resulterende genotypen.
Referanser
Mansour Tamer A, Lucot Katherine, Konopelski Sara E, Dickinson Peter J, Sturges Beverly K, Vernau Karen L, Choi Shannon, Stern Joshua A, Thomasy Sara M, Döring Sophie, Verstraete Frank J M, Johnson Eric G, York Daniel, Rebhun Robert B, Ho HsinYi Henry, Brown C Titus, Bannasch Danika L. Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds. PLoS Genet. 2018 Dec 6;14(12):e1007850. doi: 10.1371/journal.pgen.1007850. eCollection 2018 Dec.