Apa yang dimaksud dengan “Hapus”?
Hewan tersebut tidak membawa mutasi. Penyakit ini tidak akan berkembang dan tidak akan meneruskannya.
Anjing Degenerasi Sistem Ganda Anjing Pada Kerry Blue Terrier (CMSD-KBT)
The Canine Multiple System Degeneration (CMSD) DNA test is essential for Kerry Blue Terrier owners to ensure their dogs' health. CMSD is a hereditary neurological disorder affecting coordination and movement in Kerry Blue Terriers. Early genetic testing helps identify carriers and affected dogs, enabling responsible breeding decisions. By using the CMSD DNA test, breeders can reduce the risk of passing this debilitating condition to future generations. This test provides accurate, reliable results, promoting the well-being of your Kerry Blue Terrier. Protect your dog’s health with the CMSD DNA test today. Regular screening supports a healthier, happier canine companion.
Singkatan : CMSD-KBT
Mutasi yang dianalisis: SERAC1 c.1536G>A
Warisan : resesif autosom
Akronim
CMSD-KBT
Frekuensi yang diamati
Tingkat keparahan klinis
Klasifikasi klinis
Penyakit Neurologis
Mutasi yang dianalisis
SERAC1 c.1536G>A
p.(Trp512*)
p.(Trp512*)
Cara pewarisan
resesif autosom
Ringkasan tes:
Canine Multiple System Degeneration (CMSD) is a genetic disorder affecting Kerry Blue Terriers, causing progressive neurological decline. A DNA test is available to identify carriers and affected dogs, helping breeders make informed decisions. Early detection through testing can prevent the spread of this debilitating condition within the breed. Responsible breeding practices rely on these genetic insights to maintain healthy Kerry Blue Terrier populations. Overall, the CMSD DNA test is a valuable tool for canine health management.
Tersedia dari paket: Basic
Tes DNA ini disertakan mulai dari paket kami Basic — dan juga merupakan bagian dari paket Basic, Standard, Advanced, Complete.
Lihat Paket Tes DNA →Pilih paket yang paling sesuai dengan strategi pembiakan atau kesehatan hewan Anda.
Understanding Canine Multiple System Degeneration in Kerry Blue Terriers (CMSD-KBT)
Canine Multiple System Degeneration (CMSD) is a progressive neurological disorder that primarily affects Kerry Blue Terriers. This condition is characterized by the degeneration of multiple systems within the nervous system, leading to a range of debilitating symptoms that can significantly impact the quality of life of affected dogs.
Symptoms of CMSD-KBT
The symptoms of CMSD-KBT typically manifest in early to mid-adulthood, although the age of onset can vary. Common signs include balance problems, difficulty walking, and a general lack of coordination. As the disease progresses, affected dogs may exhibit muscle weakness, tremors, and a decline in overall mobility. In some cases, dogs may also experience changes in behavior, such as increased anxiety or a reluctance to engage in normal activities.
Pathophysiology of CMSD-KBT
The underlying cause of CMSD-KBT lies in genetic mutations that affect the nervous system's ability to function properly. These mutations lead to the degeneration of nerve cells, which in turn causes a breakdown of communication between the brain and the body. This disruption results in the clinical symptoms observed in affected dogs. Understanding the genetic basis of CMSD-KBT is crucial for breeders and owners, as it allows for informed decisions regarding breeding practices and the management of affected animals.
Management and Care for Affected Dogs
While there is currently no cure for CMSD-KBT, management strategies can help improve the quality of life for affected dogs. Regular veterinary check-ups are essential for monitoring the progression of the disease and addressing any health concerns that arise. Physical therapy and rehabilitation exercises can assist in maintaining mobility and strength. Additionally, providing a safe and supportive environment can help dogs cope with their symptoms and enhance their overall well-being.
Kesimpulan
Canine Multiple System Degeneration in Kerry Blue Terriers is a serious condition that requires attention from dog owners and breeders. By understanding the symptoms, underlying causes, and management strategies associated with CMSD-KBT, stakeholders can work towards improving the lives of affected dogs while making informed breeding decisions to reduce the prevalence of this condition in the breed.
Ras yang diakui untuk ujian ini: Degenerasi Sistem Ganda Anjing Pada Kerry Blue Terrier (CMSD-KBT)
- Kerry Blue Terrier
🧬 Interpretation of genotypes CMSD-KBT
Genotip
Status
🟡 N/N
Non-operator - Tanpa Risiko
🟡 N/CMSD-KBT
Operator - Tanpa Risiko
❌ CMSD-KBT/CMSD-KBT
Terkena Dampak - Berisiko
FAQ: memahami interpretasi
Apakah “Pembawa” itu serius?
Tidak. Hewan tersebut secara umum sehat tetapi dapat menularkan mutasi ke hewan tersebut keturunan.
Bagaimana jika seekor hewan “Terkena Dampak”?
Ini membawa dua salinan yang bermutasi. Tanda-tanda klinis yang diharapkan tergantung pada penyakitnya. Seharusnya tidak dibiakkan.
Mengapa ada perbedaan antara laki-laki/perempuan?
Beberapa penyakit terkait dengan seks, jadi ekspresinya bervariasi tergantung pada penyakit tersebut jenis kelamin hewan.
Memprediksi Keturunan
N/N (non-operator)
N/CMSD-KBT (Pembawa)
CMSD-KBT/CMSD-KBT (Terpengaruh)
FAQ Tes DNA
Apa yang dideteksi oleh tes DNA ini?
This DNA test detects the mutation associated with Canine Multiple System Degeneration In Kerry Blue Terrier (CMSD-KBT) in order to identify clear, carrier, or at-risk animals.
Mengapa menguji hewan yang sedang berkembang biak?
Tes DNA membantu peternak merencanakan perkawinan yang lebih aman dan mengurangi risiko penularan mutasi ke keturunannya.
Apa mode pewarisan tes ini?
Mode pewarisan yang dilaporkan untuk tes ini adalah Autosomal Resesif.
Mutasi manakah yang dianalisis dalam tes ini?
This test analyses the mutation SERAC1 c.1536G>A.
Apakah hewan pembawa pasti terkena dampaknya?
Belum tentu. Penafsirannya tergantung pada pola pewarisan dan genotipe yang dihasilkan.
Referensi
Johnson GS, Mhlanga-Mutangadura T, Morava E, Kozicz T, Taylor JF, O’Brien DP, Schnabel RD. Canine Multiple System Degeneration is Associated with Distinct SERAC1 Mutations in Two Different Dog Breeds [abstract]. Presented at the 63rd Annual Meeting of the American Society of Human Genetics in Boston, Massachusetts; 2013 Oct 22-26.