Horse Pearl (Pearl)

Discover the power of the Pearl DNA test for horses, a cutting-edge tool designed to identify the presence of the Pearl dilution gene. This genetic test helps breeders and owners understand coat color variations, ensuring accurate breeding decisions and enhancing the value of your horse. By using the Pearl DNA test, you can predict unique coat colors and patterns, improving your breeding program's precision. Easy to use and highly reliable, the Pearl test is essential for anyone serious about equine genetics. Optimize your horse’s potential with this advanced genetic screening today. Stay ahead in the equine industry with the Pearl DNA test!

Abbreviation : Pearl

Analysed mutation : SLC45A2 c.1129G/A

Inheritance : Autosomal Dominant

Acronym

Pearl

Observed frequency

Rare

Clinical classification

Coat-Related Traits

Analysed mutation

SLC45A2 c.1129G/A
p.(A377T)

Mode of inheritance

Autosomal Dominant (Incomplete)

Alternate name:

C Locus

Test summary:

The DNA test for the Pearl gene in horses identifies the presence of this unique coat color modifier. Pearl, also known as the barlink factor, affects the dilution of red pigment, resulting in distinctive cream or apricot shades. This gene is recessive, meaning a horse must inherit it from both parents to display the Pearl coloration. Testing helps breeders predict and select for desired coat colors in their breeding programs. Understanding the Pearl gene enhances genetic diversity and color possibilities in horses.

Available from the pack : Standard

This DNA test is included starting from our pack Standard — and is also part of the packs Standard, Advanced, Complete.

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Choose the pack that best fits your breeding or health strategy of your animals.

Understanding Pearl in Horses

Pearl is a unique genetic condition in horses that influences their coat color and overall appearance. It is caused by a specific mutation in the gene responsible for pigmentation, leading to a distinctive lightening of the coat in affected horses. This condition is particularly notable for its visual impact, often resulting in a strikingly beautiful horse with a cream or lightened coat.

The Genetic Basis of Pearl

The Pearl gene is a form of dilution gene, similar to those that cause palomino or buckskin colors. However, the Pearl mutation creates a unique effect that distinguishes it from other dilutions. Horses with the Pearl gene typically exhibit a softening of their coat color, which can vary depending on the base color of the horse. This gene can modify bay, chestnut, and black coats, resulting in a range of lighter shades that are often quite eye-catching.

Characteristics of Pearl-Coated Horses

Horses that carry the Pearl gene often display specific characteristics associated with this condition. Beyond the lighter coat color, these horses may have a more lustrous and shiny appearance, which can enhance their visual appeal. The genetic influence can also extend to the horse's mane and tail, which may appear lighter and more vibrant than those of non-Pearl horses.

Impact on Breeding and Future Generations

The presence of the Pearl gene can have significant implications for horse breeding. Breeders who are aware of the genetic makeup of their horses may choose to intentionally breed Pearl carriers to create offspring with this desirable trait. Understanding the inheritance patterns of the Pearl gene can help breeders make informed decisions, ultimately influencing the future aesthetics and genetics of their equine stock.

Health Considerations

While the Pearl gene primarily affects coat color, it is essential to note that it does not inherently cause any health issues in horses. Affected horses generally lead healthy lives, and the genetic condition is mainly of interest for its aesthetic qualities rather than any negative health implications. However, owners and breeders should remain informed about the overall genetic health of their horses to ensure the well-being of future generations.

Conclusion

The Pearl gene is a fascinating aspect of equine genetics that adds to the complexity and beauty of horse breeding. With its unique effects on coat color and the potential for creating stunningly beautiful horses, understanding the Pearl condition can enhance the appreciation of equine diversity. As horse enthusiasts and breeders continue to explore the implications of this gene, the legacy of Pearl-coated horses is sure to captivate many for years to come.

Breed recognized for the test : Pearl (Pearl)

American Paint
Lusitanian
Purebred Spanish
Quarter Horse

Interpretation of genotypes Genotype Status Learn more about the interpretation of genotypes FAQ: understanding the interpretation of result What does “Clear” mean? The animal does not carry the mutation. It will not develop the disease and will not pass it on. Is a “Carrier” serious? No. The animal is generally healthy but can transmit the mutation to its offspring. What if an animal is “Affected”? It carries two mutated copies. Clinical signs are expected depending on the disease. It should not be bred. Why are there differences between male / female? Some diseases are sex-linked, so their expression varies depending on the animal’s sex. The animal has two normal copies of the gene. No risk of developing or transmitting the disease. Heterozygous carrier: one mutated copy. The animal is usually not clinically affected but can pass the mutation to offspring. Male carrier or affected depending on the inheritance mode. Males have only one X or Y chromosome. Heterozygous female carrier: one mutated copy. She can pass the mutation on and may sometimes show mild clinical signs depending on the condition. Two mutated copies of the gene. The animal is at risk of developing the associated condition.

🧬 Interpretation of genotypes Pearl

Genotype

Status

🟡 N/N

Non-carrier - No effect

🟡 N/Prl

Carrier - Champagne

❌ Prl/Prl

Affected - Champagne

FAQ: understanding the interpretation

What does “Clear” mean?

The animal does not carry the mutation. It will not develop the disease and will not pass it on.

Is a “Carrier” serious?

No. The animal is generally healthy but can transmit the mutation to its offspring.

What if an animal is “Affected”?

It carries two mutated copies. Clinical signs are expected depending on the disease. It should not be bred.

Why are there differences between male / female?

Some diseases are sex-linked, so their expression varies depending on the animal’s sex.

Genotype Forecast for Offspring Mother Father Non-carrier Carrier Affected Favorable cross: majority Carrier risk is predominant. Majority affected Filter by mother's genotype Filter by father's genotype All Predict Offspring The animal has two normal copies of the gene. No risk of developing or transmitting the disease. Heterozygous carrier: one mutated copy. The animal is usually not clinically affected but can pass the mutation to offspring. Male carrier or affected depending on the inheritance mode. Males have only one X or Y chromosome. Heterozygous female carrier: one mutated copy. She can pass the mutation on and may sometimes show mild clinical signs depending on the condition. Two mutated copies of the gene. The animal is at risk of developing the associated condition.

Predict Offspring

Filter by mother's genotype Filter by father's genotype

N/N (Non-carrier)

N/Prl (Carrier)

Prl/Prl (Affected)

DNA Test FAQ

What does this DNA test detect?

This DNA test detects the mutation associated with Pearl in order to identify clear, carrier, or at-risk animals.

Why test a breeding animal?

DNA testing helps breeders plan safer matings and reduce the risk of transmitting the mutation to offspring.

What is the inheritance mode of this test?

The inheritance mode reported for this test is Autosomal Dominant.

Which mutation is analysed in this test?

This test analyses the mutation SLC45A2 c.1129G/A.

Is a carrier animal necessarily affected?

Not necessarily. Interpretation depends on the inheritance pattern and the resulting genotype.

References

Sevane N, Sanz C R, Dunner S. Explicit evidence for a missense mutation in exon 4 of SLC45A2 gene causing the pearl coat dilution in horses. Anim Genet. 2019 Jun;50(3):275-278. doi: 10.1111/age.12784. Epub 2019 Apr 10.

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