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Pas Primarni glaukom otvorenog ugla kod Basset Fauve De Bretagne (POAG-BFB)


Discover the importance of DNA testing for Primary Open Angle Glaucoma (POAG) in Basset Fauve de Bretagne dogs. This hereditary condition can lead to serious vision problems, making early detection crucial. By utilizing a DNA test, breeders and pet owners can identify at-risk individuals and implement preventive measures. Understanding your dog’s genetic predisposition allows for better health management and informed breeding decisions. Ensure the long-term well-being of your Basset Fauve de Bretagne by considering a genetic test for POAG. Protect your furry friend’s vision and quality of life today! Explore reliable testing options to stay ahead of this genetic condition.

skraćenica : POAG-BFB
Analizirana mutacija: ADAMTS17 c.1552G>A
nasljeđe : Autosomno recesivno

Akronim

POAG-BFB

Uočena frekvencija

Rijetko

Klinička težina

Umjereno

Klinička klasifikacija

Oftalmološke bolesti

Analizirana mutacija

ADAMTS17 c.1552G>A
p.(G518S)

Način nasljeđivanja

Autosomno recesivno

Sažetak testa:

The DNA test for Primary Open Angle Glaucoma (POAG) in Basset Fauve de Bretagne is a crucial tool for breeders and veterinarians. This genetic test helps identify dogs at risk of developing this progressive eye condition, which can lead to vision loss. By screening for specific genetic markers, responsible breeding practices can be implemented to reduce the incidence of POAG in future generations. Early detection through DNA testing allows for timely interventions, improving the quality of life for affected dogs. Ultimately, this test contributes to the overall health and longevity of the breed.

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Understanding Primary Open Angle Glaucoma (POAG) in Basset Fauve De Bretagne

Primary Open Angle Glaucoma (POAG) is a significant ocular condition that affects the intraocular pressure in dogs, particularly noted in breeds like the Basset Fauve De Bretagne. This condition is characterized by a gradual increase in intraocular pressure due to impaired drainage of aqueous humor, leading to potential optic nerve damage and vision loss if not addressed promptly.

Genetska osnova POAG

Research has indicated that there is a hereditary component to POAG, suggesting that certain genetic mutations may predispose individuals to developing this condition. The identification of specific genetic markers associated with POAG can assist breeders in making informed decisions to reduce the prevalence of this glaucoma type within the breed.

Clinical Signs and Diagnosis

The clinical signs of POAG can be subtle at first, often including increased tear production, cloudiness of the cornea, and behavioral changes such as reluctance to engage in activities that require good vision. As the condition progresses, dogs may exhibit signs of pain, such as squinting or rubbing their eyes. Early diagnosis is crucial for effective management and to prevent irreversible damage to the optic nerve.

Opcije tretmana

Treatment for POAG typically involves a combination of medical management and surgical intervention. Medications may be prescribed to lower intraocular pressure, while surgical options can include procedures to improve fluid drainage from the eye. The choice of treatment depends on the severity of the condition and the individual dog's needs.

Važnost genetskog testiranja

Genetic testing for POAG in Basset Fauve De Bretagne serves as a crucial tool for responsible breeding practices. By identifying carriers of the genetic mutations associated with POAG, breeders can make informed breeding choices that may help reduce the incidence of this condition within the breed. This proactive approach contributes to the overall health and well-being of future generations of Basset Fauve De Bretagne dogs.

Zaključak

Primary Open Angle Glaucoma is a serious condition that can lead to significant health issues if left untreated. Understanding the genetic factors involved in this disease, along with the clinical signs and treatment options, is essential for dog owners and breeders alike. Through genetic testing and responsible breeding practices, the impact of POAG can be mitigated, leading to healthier lives for affected breeds.


Rasa priznata za test: Primarni glaukom otvorenog ugla kod Basset Fauve De Bretagne (POAG-BFB)

  • Basset Fauve de Bretagne

🧬 Interpretation of genotypes POAG-BFB

Genotip
Status
🟡 N/N
Non-carrier - Bez rizika
🟡 N/POAG-BFB
Nosilac - Bez rizika
❌ POAG-BFB/POAG-BFB
Pogođeno - u opasnosti

FAQ: razumijevanje interpretacije

Šta znači "Jasno"?

Životinja ne nosi mutaciju. To neće razviti bolest i neće ga prenijeti dalje.

Da li je "prevoznik" ozbiljan?

Ne. Životinja je općenito zdrava, ali može prenijeti mutaciju na svoju potomstvo.

Šta ako je životinja “pogođena”?

Nosi dvije mutirane kopije. Klinički znakovi se očekuju ovisno o bolest. Ne treba ga uzgajati.

Zašto postoje razlike između muškaraca i žena?

Neke bolesti su spolno vezane, tako da njihova ekspresija varira u zavisnosti od toga spol životinje.



Predvidi potomstvo

N/N (Non-carrier)
N/POAG-BFB (Carrier)
POAG-BFB/POAG-BFB (Pogođeno)

DNK test FAQ

Šta otkriva ovaj DNK test?

This DNA test detects the mutation associated with Primary Open Angle Glaucoma In Basset Fauve De Bretagne (POAG) in order to identify clear, carrier, or at-risk animals.

Zašto testirati rasplodnu životinju?

DNK testiranje pomaže uzgajivačima da planiraju sigurnije parenje i smanjuju rizik od prenošenja mutacije na potomstvo.

Koji je način nasljeđivanja ovog testa?

Način nasljeđivanja prijavljen za ovaj test je autosomno recesivan.

Koja se mutacija analizira u ovom testu?

This test analyses the mutation ADAMTS17 c.1552G>A.

Da li je životinja nosilac nužno pogođena?

Nije nužno. Tumačenje zavisi od obrasca nasljeđivanja i rezultirajućeg genotipa.


Reference

Oliver James A C, Forman Oliver P, Pettitt Louise, Mellersh Cathryn S. Two Independent Mutations in ADAMTS17 Are Associated with Primary Open Angle Glaucoma in the Basset Hound and Basset Fauve de Bretagne Breeds of Dog. PLoS One. 2015 Oct 16;10(10):e0140436. doi: 10.1371/journal.pone.0140436. eCollection 2015.

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Primary Open Angle Glaucoma In Basset Fauve De Bretagne (POAG)
Primary Open Angle Glaucoma In Basset Fauve De Bretagne (POAG) - MyLabDNA
Discover the DNA test for Primary Open Angle Glaucoma in Basset Fauve De Bretagne dogs. Ensure your pet's health with early detection!
Primary Open Angle Glaucoma In Basset Fauve De Bretagne (POAG)
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Primary Open Angle Glaucoma In Basset Fauve De Bretagne (POAG) - MyLabDNA
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Discover the DNA test for Primary Open Angle Glaucoma in Basset Fauve De Bretagne dogs. Ensure your pet's health with early detection!
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