「清晰」係咩意思？
呢隻動物唔會攜帶呢個突變。佢唔會發病 同埋唔會傳落去。
馬 Splashed White SW4 (SW4)
The Splashed White SW4 (SW4) DNA test is essential for horse breeders and enthusiasts aiming to identify this unique coat pattern gene. This genetic test detects the presence of the SW4 variant, responsible for the distinctive splashed white markings in horses. Understanding the SW4 gene helps in predicting coat colors and ensuring accurate breeding outcomes. The test is quick, reliable, and can be performed using a simple hair or blood sample. By using the Splashed White SW4 DNA test, breeders can enhance their breeding programs and maintain the health and diversity of their horses. Accurate identification of the SW4 gene also aids in registration and pedigree verification. Invest in the SW4 DNA test today to unlock valuable insights into your horse’s genetics.
縮寫： SW4
分析咗嘅突變： PAX3 c.95C/G
遺產 ： Autosomal Dominant
首字母縮寫
SW4
觀察到嘅頻率
臨床分類
同外套有關嘅特徵
分析咗嘅突變
PAX3 c.95C/G
p.(P32R)
p.(P32R)
繼承方式
Autosomal Dominant (Incomplete)
測試摘要：
The Splashed White SW4 (SW4) DNA test identifies a specific gene variant responsible for the Splashed White coat pattern in horses. This pattern is characterized by large white markings that appear as if the horse has been dipped in white paint, often with blue eyes. The SW4 variant is one of several mutations linked to this distinctive look. Testing for SW4 helps breeders predict coat colors and maintain genetic diversity. Understanding this gene also aids in managing potential health concerns associated with Splashed White patterns.
喺包裝入面有得買： Standard
呢個 DNA 測試由我哋嘅包裝開始包括喺入面 Standard — 而且亦都係包嘅一部分 Standard, Advanced, Complete。
查看 DNA 檢測包 →揀最適合你嘅動物嘅繁殖或者健康策略嘅群體。
Introduction to Splashed White SW4 (SW4)
Splashed White SW4 (SW4) is a genetic condition observed in horses, primarily characterized by distinctive coat patterns resulting from a specific mutation. This condition is part of a broader category known as white markings that horses can exhibit, which are often associated with various genetic factors. Understanding SW4 is essential for breeders and owners who aim to manage and maintain the health and appearance of their equine companions.
Genetic Basis of Splashed White SW4
The SW4 condition is caused by mutations in the MITF gene, which plays a crucial role in the development of melanocytes—cells responsible for pigment production in the skin and hair. The specific mutation associated with SW4 leads to a unique expression of white markings on the horse's coat, which can vary significantly from one individual to another. These markings typically present as large patches of white that may cover parts of the horse's body, often leaving areas of colored hair.
Phenotypic Characteristics
Horses with the SW4 mutation exhibit a range of phenotypic characteristics, including varying degrees of white markings. The coat patterns can include large, irregularly shaped white areas that may extend over the face, legs, and body. The presence of these markings can impact the horse's overall appearance and is often a point of interest for breeders and enthusiasts within the equine community.
Health Implications
While the Splashed White SW4 condition is primarily noted for its aesthetic implications, it is important to consider potential health issues that may arise. Horses carrying the SW4 mutation may be predisposed to certain congenital conditions, particularly those affecting hearing and vision. Regular veterinary check-ups and monitoring for any signs of health complications are advisable for horses with this genetic trait.
DNA 測試嘅重要性
DNA testing for the SW4 mutation serves an important role in equine breeding programs. By identifying horses that carry the SW4 mutation, breeders can make informed decisions about mating practices to manage and potentially minimize the occurrence of undesirable traits. This genetic insight allows for the preservation of specific breed characteristics while considering the health and welfare of the horses involved.
結論
Understanding the Splashed White SW4 condition provides valuable insights into the genetic diversity and physical characteristics of horses. It highlights the importance of genetics in breeding practices and the potential health implications associated with specific mutations. As the equine community continues to advance in genetic research, the role of DNA testing will remain pivotal in promoting responsible breeding and ensuring the overall well-being of horses.
測試認可嘅品種： Splashed White SW4 (SW4)
- Appaloosa
🧬 Interpretation of genotypes SW4
基因型
地位
🟡 N/N
非載波 - 冇效果
🟡 N/SW4
Carrier - Splashed White
❌ SW4/SW4
Affected - Splashed White
常見問題：理解解釋
「承載者」係咪認真？
唔係。隻動物一般都係健康嘅，但係可以將突變傳染畀佢 後代。
如果一隻動物係「受影響」嘅話點算好？
佢有兩個突變嘅副本。預計會有臨床症狀，視乎情況而定 個病。唔應該繁殖。
點解男 / 女有分別？
有啲疾病係同性別有關，所以佢哋嘅表現會因疾病而異 動物嘅性別。
預測後代
N/N （%e9%9d%9e%e6%b5%81%e5%8b%95%e7%b6%b2%e7%b5%a1%e4%be%9b%e6%87%89%e5%95%86）
N/SW4 （航空公司）
SW4/SW4 （受影響）
DNA 測試常見問題
呢個 DNA 測試可以檢測到啲咩？
This DNA test detects the mutation associated with Splashed White SW4 (SW4) in order to identify clear, carrier, or at-risk animals.
點解要測試一隻繁殖動物？
DNA 檢測有助養殖者計劃更安全嘅交配，同埋減低將突變傳播畀後代嘅風險。
呢個測試嘅繼承模式係點？
The inheritance mode reported for this test is Autosomal Dominant.
呢個測試會分析邊個突變？
This test analyses the mutation PAX3 c.95C/G.
載體動物係咪一定會受到影響？
唔一定。解釋取決於遺傳模式同所產生嘅基因型。
參考文獻
Hauswirth Regula, Jude Rony, Haase Bianca, Bellone Rebecca R, Archer Sheila, Holl Heather, Brooks Samantha A, Tozaki Teruaki, Penedo Maria Cecilia T, Rieder Stefan, Leeb Tosso. Novel variants in the KIT and PAX3 genes in horses with white-spotted coat colour phenotypes. Anim Genet. 2013 Dec;44(6):763-5. doi: 10.1111/age.12057. Epub 2013 May 9.