馬 Lethal White Overo Syndrome (LWO)

Overview of Lethal White Overo Syndrome (LWO)

Lethal White Overo Syndrome (LWO) is a genetic disorder found in horses, particularly affecting those with a specific coat color pattern known as the overo pattern. This condition is caused by a mutation in the gene responsible for the development of certain neural crest cells, which play a crucial role in the formation of the digestive tract and pigmentation. Horses affected by LWO typically exhibit certain visible characteristics, but the most significant issues arise internally, leading to severe health complications.

症狀同臨床徵兆

The most notable clinical signs of Lethal White Overo Syndrome manifest shortly after birth. Affected foals are usually born with a distinctive white coat and blue eyes. However, they face major health challenges, primarily related to their gastrointestinal system. The most critical symptom is the failure of the foal to pass feces, indicating a lack of proper intestinal development. This can lead to colic and, ultimately, death within days of birth if not addressed.

Genetics and Inheritance

Lethal White Overo Syndrome is inherited in an autosomal recessive manner, meaning that both parents must carry the gene mutation for an offspring to be affected. Horses that are carriers of the LWO gene may not display any symptoms themselves, but when two carriers breed, there is a 25% chance that the resulting foal will inherit the condition. Understanding the genetics behind LWO is crucial for breeders who wish to avoid producing affected foals.

DNA 測試嘅重要性

DNA testing for Lethal White Overo Syndrome is essential for responsible breeding practices. By identifying carrier horses, breeders can make informed decisions to minimize the risk of producing affected foals. This proactive approach not only helps in maintaining the health of the horses but also promotes ethical breeding standards within the equine community. The availability of DNA tests has significantly contributed to reducing the incidence of LWO in breeding programs.

結論

Lethal White Overo Syndrome is a serious genetic condition that poses significant risks to foals born with the overo coat pattern. Through genetic testing and responsible breeding practices, the equine industry can work towards reducing the occurrence of this syndrome. Awareness and education about LWO are vital for breeders, veterinarians, and horse owners to ensure the health and well-being of affected horses and prevent the continuation of this genetic disorder.

測試認可嘅品種： Lethal White Overo Syndrome (LWO)

• Abeia
• Abyssinian
• Adaev
• Aegidienberger
• Akhal-Teke
• Akhaltekinskaya
• Alberta Wild Horse
• Alogo kypriakis ektrofis
• Alpine
• Alt-Württemberger
• Altai
• American Cream Draft
• American Crème and White Horse
• American Miniature
• American Miniature Horse
• American Paint
• American Paint Horse
• American quarter horse
• American Saddle Horse
• American Shetland Pony
• American Sugarbush Harlequin Draft
• American Walking Pony
• American White Draft Horse
• Amurskaya
• Anatolian
• Andalusian
• Andravida
• Anglo European
• Anglo-Arab
• Anglo-Kabarda
• Anglo-Kabardiner
• Anglo-Norma
• Appaloosa
• Appaloosa Pony
• Arab
• Arab Horse
• Araber
• Arabian purebreed
• Arabisches Halbblut
• Arabo Friese Paard
• Ardennes
• Aréwa 1
• Arewa 2
• Argentine Criollo
• Arravani
• Asno
• Assateague Pony
• Asturcón
• Atheland
• Augeron
• Australian Brumby
• Australian Draught Horse
• Australian Pony
• Australian Stockhorse
• Australian Waler
• Auxois
• Avarskaya
• Ayvacik Pony
• Azteca
• Baguio light horse
• Baguio pony
• Bahr-El-Ghazal
• Baixadeiro
• Bajau
• Bakhtiari
• Baladi Egyptian
• Bale
• Bali
• Balkar
• Baluchi
• Banat
• Bandiagara
• Bangladesh native horse
• Barb
• BARBRI
• Bardigiano
• Bardigiano pony
• Barkol
• Barock-Reitpferd
• Barra Pony
• Barut
• Bashkir Curly
• Bashkirskaya
• Basotho Pony
• Basseri
• Batak
• Bavarian Warmblood
• Beberbecker
• Beledougou
• Belgian Draft
• Belgian Draft Horse
• Belgian Sport Horse
• Belgian Warmblood
• Belgische Rijpony
• Belorusskaya
• Berber
• Berrichon
• Bhirum Pony
• Bhotia Pony
• Bima
• Bityug
• Black and White Frisian
• Blazer Horse
• Bobo
• Boer
• Boeta
• Bohai
• Borana
• Bornu
• Bose
• Bose - Baise Pony
• Bosnian
• Bosnian horse
• Bosnian Mountain Horse
• Bosnian Pony
• Boulonnais
• Bourbonnais
• Brabanter
• Brandenburg
• Brasileiro de Hipismo
• Breton
• British Falabella
• British Piebald
• British Riding Pony
• British Show Horse
• British Skewbald
• British Spotted Pony
• British Warmblood
• Brittany Triangle
• Broomtail
• Brumbie
• Buckskin
• Budyonny
• Bulgarian Heavy Draft Horse
• Bulgarian sport horse
• Burgdorfer
• Burguete
• Burmese
• Buryatskaya
• Busa Pony
• Buzkashi
• Byryatskaya
• Cabadin
• Caballo Cubano de Paso
• Caballo de Deporte Español
• Caballo de las Retuertas
• Caballo de Monte de País Vasco
• Caballo de Pura Raza Chilena
• Caballo de trote
• Caballo Deportivo Uruguayo
• Cabalo de Pura Raza Galega
• Calvinia
• Camargue
• Camarillo White Horse
• Cambodian
• Campeiro
• Campolina
• Canadian
• Canadian Warmblood
• Canelón
• Canik
• Cape Harness
• Cape Horse
• Carolina Marsh Tacky
• Caspian
• Castillonnais
• Cavall Mallorquí
• Cavall Pirinenc Català
• Cavallino della Giara
• Cavallino di Monterufoli
• Cavallo Agricolo Italiano da Tiro Pesante Rapido
• cavallo Appenninico
• Cavallo Bardigiano
• Cavallo del Catria
• Cavallo del Delta
• Cavallo del Ventasso
• Cavallo Maremmano
• Cavallo Pentro
• Cavallo Romano della Maremma Laziale
• Cayuse
• Ceskomoravsky belgicky kun
• CH-Warmblut
• Chadian
• Chaidamu
• Chakouyi
• Charysh
• Chernomorskaya
• Cheval Camarque
• Cheval Corse
• Cheval de Nioro
• Cheval de race Auvergne
• Cheval de sport Anglo-normand
• Cheval du Vercors de Barraquand
• Chickasaw
• Chilkovskaya
• ChinCôteague Pony
• Chummarti
• Chumyshskaya Porodnaya Gruppa
• Chuvashskaya
• Chwal
• Chyanta
• Cimarron
• Cleveland Bay
• Clydesdale
• Cob
• Coffin Bay Pony
• Colombiano
• Colorado Ranger
• Coloured Horse and Pony
• Comtois
• Comune
• Conestoga
• Connemara Pony
• Cossack
• Costarricense de Paso
• Costeño
• Cracker
• Crème
• Creole
• Crete
• Criollo
• Criollo Altiplánico
• Criollo chilote
• Criollo Colombiano
• Criollo de paso
• Criollo de trote
• Criollo Hondureño
• Criollo Militar
• Criollo Oriental
• Criollo Paraguaya
• Criollo Uruguayo
• Crioulo
• Croatian Coldblood horse
• Croatian Posavina horse
• Croatian trotter
• Cruzado
• Cruzado Iberico
• Cruzado Portugues
• Çukurova
• Curly Horse
• Cushendale
• Czech Riding Pony
• Czech Warmblood
• Dagestan Pony
• Dahmaa
• Dales
• Dales Pony
• Danish Warmblood
• Danubian horse
• Dareshuri
• Darkhad
• Dartmoor Hill Pony
• Dartmoor Pony
• Datong
• Dawand
• Deccani
• Deli-Orman
• Deutscher Falbe
• Deutscher Tigerschecke
• Deutsches Classic Pony
• Deutsches Partbred Shetland Pony
• Deutsches Pferd
• Deutsches Pinto Barockpferd
• Deutsches Polopferd
• Deutsches Reitpony
• Deutsches Sportpferd
• Devon Pack Horse
• Dilbaz
• Dobrogeana
• Doelahest
• Dombi
• Don
• Dongola
• Donkey
• Dosanko
• Drumhorse
• Dülmener
• Dutch Warmblood
• Eastbulgarian Horse
• Ebian
• Edelblut-Friese
• Edelbluthaflinger
• Einsiedler
• English Halbblut Horse
• English Riding Pony
• English Spotted Pony
• Eriskay
• Erlunchun
• Estonian Draft
• Estonian Heavy Draught
• Estonian Native Horse
• Europäischer Appaloosa-Pony
• Europäischer Tigerschecke
• Europäischer Westernpferd
• European Warmblood
• Exmoor Pony
• Faeroes Pony
• Færøsk hest
• Falabella Pony
• Fell Pony
• Fina sangre francés
• Finnhorse
• Finnish Riding Pony
• Finnish warmblood
• Fjord
• Fjord Horse
• Flamand
• Fleuve
• Flores
• Fouta
• FoutankÃ
• Franches-Montagnes
• Frederiksborg Horse
• Frederiksborger
• Freiberger
• French Chaser
• French Coach
• French Saddlebred
• French Trotter
• French Warmblood
• Friesian
• Furioso-Northstar
• Galiceno
• Galloway Pony
• Galshar
• Ganzi
• Garrano
• Gayo
• Gazal
• Gelder horse
• Gemlik
• German Bessarabian
• German Coach
• German Riding Pony
• German Warmblood
• Giawf
• Gidran
• Glasinacki
• Gocan
• Goonhilly
• Gotland Pony
• Great Horse
• Greenbank Army
• Groninger horse
• Guanzhong
• Guba
• Guizhou
• Guy Fawkes River National Park Brumby
• Hackney
• Hackney Pony
• Haddian
• Haflinger
• Hannoveraner Halbblut
• Hannoversches Kaltblut Schleswiger Ursprungs
• Hanoverian
• Hausa
• Hebridean Pony
• Heihe
• Heilongjiang
• Henan Light Draught
• Henson
• Hequ
• Herati
• Hessen
• Highland Pony
• Hinis
• Hinisin Kolu Kisasi
• Hirzai
• Hispano-Árabe
• Hispano-Bretón
• Hodh
• Holstein
• Holsteiner
• Horro
• Horse
• Hungarian Sport Horse
• Hutsul
• Ialomita
• Iberoamericana
• Iberoamericano
• Icelandic Horse
• Internationales Oldenburger Springpferd
• Irish Cob
• Irish Cob Crossbred
• Irish Cobb
• Irish Draught
• Irish Miniature
• Irish Pony
• Irish Sport Horse
• Irish Sporthorse
• Irish Warmblood
• Islandic Horse
• Iyi
• Jabe
• Jaca Navarra
• Jaf
• Japanese Draft
• Javakhuri Harness Horse
• Jawa
• Jeju Horse
• Jianchang
• Jilin
• Jinjiang
• Jinzhou
• Jofi
• Jumli
• Jutland Horse
• Kabarda
• Kachchhi Sindhi
• Kafa
• Kahilan
• Kaimanawa ' Wild' Horse
• Kallblodstravare
• Kalmutskaya
• Kanata Pony
• Karabair
• Karabakh
• Karacabey Halfbred Arab
• Karacabey-Nonius
• Karachai
• Karakachan horse
• Karatschaewer
• Karel'skaya
• kasaški konj
• Kathiawari
• Kazakh
• Keheilan
• Kentucky Mountain Saddle
• Kerqin
• Kerry Bog Pony
• Kiger Mustang
• Kinsky Pferd
• Kirgiz
• Kisber Halfbred
• Kiso
• Kladruby
• Klassiek Gelderlander paard
• Kleines Deutsches Pony
• Kleines Deutsches Reitpferd
• Knabstrupper
• Knabstrupper Horse
• Kohband
• Konik Pony
• Kosciusko Brumby
• Koto-Koli Pony
• Krk Island pony
• Kuda Padi
• kuda-Pacu Indonesia
• Kumykskaya
• Kun Kinsky
• Kundido feral
• Kuningan
• Kurdi
• Kushum
• Kushumskaya
• Kustanai
• Kuznetskaya Porodnaya Gruppa
• KWPN
• L'arabe-barbe
• Lac La Croix Indian Pony
• Lämminverinen Ravihevonen
• Landais
• Latvian Draught
• Latvian Harness
• Latvijas š?irne
• Lavradeiro
• Le poney des Mogods
• Lehmkuhlener Pony
• Lenkoran
• Leonharder
• Leutstettener
• Lewitzer
• Lezginskaya
• Lichuan
• Lipitsa
• Lipizzan horse
• Lippizan
• Lithuanian Cart
• Lithuanian Heavy Draft
• Ljutomerski kasac
• Llanero
• Local Horse
• Local Moldavian
• Locale
• Loire
• Lokaiskaya
• Lombok
• Long Mynd
• Losina
• Lovetskaya
• Lower Caucasus
• Lundy
• Lusitanian
• M' Par
• M'bayar
• Ma
• Ma?opolski
• Ma?opolski w starym typie
• Magyar Hidegvéru
• Maine
• Makasar
• Makra
• Malakan
• Maneghi
• Mangalarga
• Mangalarga Marchador
• Manipuri Pony
• Manx
• Marajoara
• Maremmano
• Marismeña
• Marwari
• Mazari
• Mecklenburg
• Media sangre
• medzimurski konj
• Megruli Horse
• Merak Saktenpata
• Merens Pony
• Mexican Pony
• Mezenskaya
• Minahasa
• Mini Shetland Pony
• Miniature
• Miniature Horse
• Miniature Mediterranean Donkey
• Miniature Pony
• Miniatures
• Minusinsk
• Misaki
• Misko
• Missouri Fox Trotter
• Missouri Fox Trotting Horse
• Mixed Breed
• Miyako
• Moldovenesca
• Monchina
• Mongolian
• Mongolian - Ujumqin
• Montana Traveler
• Moravsky teplokrevnik
• Morgan
• Morocco Spotted
• Morochuca
• Morochuco Chumbivilcano
• Mossi
• Mountain pony
• Mugalzhar
• Mulassier du Poitou
• Murgese
• Murinsulaner horse
• Mustang
• Myngad
• Mytilene Pony
• Namagdi National Park Brumby
• Namaqua Pony
• Namib Horse
• Nanbu
• Napoletano
• Narragansett Pacer
• Narym
• Native Racehorse
• Nederlands Appaloosa Pony
• Nederlands Mini Paarden
• Nefza Pony
• New Forest Pony
• New Kirgiz
• New Lijiang
• Newfoundland Pony
• Newolexandrian heavy draft
• Ngua Noi
• Niederländisches Kaltblut
• Ningqiang
• Nivernais
• Nogai
• Noma
• Nonius
• Nooitgedacht Pony
• Nordestino
• Nordlandshest lyngshest
• Nordsvensk Brukshäst
• Nordsvensk travare
• Noric
• Norman Cob
• Norsk varmblod
• Northern Ardennes
• Novoaltaiskaya
• Obva
• OISK
• Old Kladruby Horse
• Oldenburg
• Omarqoub
• Ondorshil
• Onega
• Orlov Saddle Horse
• Orlov Trotter
• Österreichisches Kaltblut
• Österreichisches Warmblut
• Ostfriesisch-altoldenburgisches Schweres Warmblut
• Ostpreußisches Warmblut Trakehner Abstammung
• Ox-Araber
• Palomino
• Palouse
• Pantaneiro
• Pantanero
• Part Bred Cob
• Paso Fino
• Paso Iberoamerikano
• Paso Peruano
• Paso Pferd
• Patibarcino
• Pechorskaya
• Percheron
• Persano
• Peruana
• Peruano de paso
• Peruvian Paso
• Pfalz Ardenner Kaltblut
• Philippine Pony
• Piebald and Skewbald
• Pindos
• Pineia- Geogalidiko- Georgaludiko
• Pinkafö
• Pinto
• Pleven Horse
• Podveleski
• Poitevin
• Poitou Donkey
• Polesskaya
• Polish Coldblood
• Polish Konik
• Polish Trakehner
• Polish Trotter
• Polo Argentino
• Polski ko? szlachetny pó?krwi
• Ponei da Terceira
• Poney
• Poney du Logone
• Poney français de selle
• Poni
• Ponny Welch
• Pony
• Pony di Esperia
• Pony Of the Americas
• Ponys
• Posavina
• Pottok
• Priobskaya
• Przewalski Horse
• Puno Pony
• Pura raza española
• Purebred Spanish
• Puro Sangue Orientale
• Puruca
• Qashqai
• Qatgani
• Qazal
• Quarab Horse
• Quarter Horse
• Quarter Pony
• Racking Horse
• Rajshahi Pony
• Rancher
• Rassegruppe der Deutschen Reitpferde
• Rassegruppe Schweres Warmblut
• Raza Iberica - Portugiesisches Sportpferd
• Raza Menorquina
• Rheinish Westphalian Draught Horse
• Rhenish Warmblood
• Riding Horse
• Rila Mountain
• Rocky Mountain
• Romanian Draft
• Romanian Mountain
• Romanian Sport horse
• Romanian Trotter
• Rostopchin
• Rottal
• Rumelian Pony
• Russian
• Russian Courser
• Russian Draft
• Russian Heavy Draft
• Russian Trotter
• Russkaya krovnaya verkhovaya
• Russkii Tyazhelovoz
• SA Miniature Horse
• SA Sporting horse
• SA Warm Blood
• Sabih
• Sable Island Pony
• Sachsen-Anhaltiner Warmblut
• Sächsisch-Thüringisches Schweres Warmblut
• Sächsisches Warmblut
• Saddlebred
• Sahel
• Salernitano
• Samand
• Sandelwood
• Sanfratellano
• Sanhe
• Saône-et-Loire
• Saqallwiya
• Sarcidano
• Schleswig Coldblood
• Schwarzwälder Kaltblut
• Schweres Warmblut Dänemark
• Selale
• Sella Italiano
• Selle Francais Horse
• Senne
• Serrana
• Shagya Arab
• Shan Pony
• Shandan
• Shetland Pony
• Shirazi
• Shire
• Shirvan
• Shweimaa
• Siglavi
• Silesian Horse
• Silesian Norik
• Silla Uruguayo
• Silver Dapple
• Sistani
• Skewbald Piebald
• Skyros Pony
• Śląski w starym typie
• Slovak Warmblood
• Slovak Warmblood Horse
• slovenski hladnokrvni konj
• slovenski toplokrvni konj
• Slovenský športový pony
• Small horse
• Sokolski
• Somali Pony
• Songhoï
• Sorraia
• Soudan
• Soviet Heavy Draft
• Soviet Saddle
• Spanish Barb
• Spanish Horse
• Spanish Jennet
• Spiti Pony
• Sport
• Sport Horse
• Sport Pony
• Spotted
• Spotted Saddle Horse
• Srednekolymskaya
• Sri Lankan Pony
• Standard Bred Trotting Horse
• Standardbred
• Standardbred x Tennessee Walking Horse cross
• Stara Planina
• Stonewall Sporthorse
• Streletska
• Styrian Horse
• Sudan Country-Bred
• Süddeutsches Kaltblut
• Suffolk
• Sulebawa
• Sumbar-Sandel-Arab
• Sumbawa
• Sunicho
• Svensk ardennerhäst
• Svensk varmblodig travare
• Swedish Riding Pony
• Swedish Warmblood
• Syrian
• Sztumski
• Tadzhikskaya Verkhovaya
• Tagaytay light horse
• Tagaytay pony
• Taleshi
• Talon
• Tanghan
• Tarai Pony
• Taropud
• Tarpan
• Tattu
• Tavdinskaya
• Tawleed
• Tennessee Walking Horse
• Tersk
• Tes
• Thessalia
• Thoroughbred
• Thüringer Warmblut
• Tibetan - Sikang Pony
• Tibetan Pony
• Tieling Draught
• Tiger Horse
• Timor Pony
• Tinker
• Tiree
• Tokara Pony
• Tolfetano
• Tölter
• Tomskaya
• Tooraq
• Tori hobune
• Tori Horse
• Torian
• Toriyskaya
• Tory
• Traber
• Traditional Gypsy Cob
• Trait du Nord
• Trakehner
• Transylvaneana
• Travere
• Trocha Pura Colombiana
• Trocha y Galope Reunido Colombiano
• Trotador Español
• Trote de andar
• Trottatore Italiano
• Trotter
• Trotter horse
• Trotteur Belge
• Trottingbred Horse
• Tsushima
• Tswana
• Tuigpaard
• Turáni ló
• Turkemin
• Turkish Arab
• Tushuri Horse
• Tuvinskaya
• Tuvinskaya upryazhnaya
• Ukrainian Saddle
• Ungarisches Kaltblut
• Unknown
• Uzunyayla
• Vardy
• Verkhne-Eniseiskaya
• Viking
• Vladimirskaya
• Vladimirskaya Tyazhelovoznaya
• Vollblut
• Vollblutaraber
• Voronezhskaya upryazhnaya
• Vyatskaya
• Waler
• Warlander
• Warmbloed
• Warmblood
• Warmblood British Warmblood
• Warmblutschecken
• Waziri
• Welara Pony
• Wels
• Welsh
• Welsh Cob
• Welsh Mountain
• Welsh Mountain Pony
• Welsh Pony
• Welsh Pony of Cob Type
• Wenshan
• West African Barb
• West African Dongola
• West African Pony
• Western Sudan Pony
• Westphalian Warmblood
• Wielkopolski
• Wilekopolski w starym typie
• Wilwal
• Workhorse
• Württemberger Warmblut
• Xiangfen
• Xilinguole
• Xinihe
• Yabu
• Yagha
• Yakutskaya
• Yanqi
• Yargha
• Yiwu
• yomood
• Yonaguni
• Yongning
• Yorkshire Coach Horse
• Yunnan - Lijiang
• Yunnan pony
• Yushu
• Yuta
• Zabaykalskaya
• Zangersheide
• Zaniskari Pony
• Žemaitukai
• Zhangbei
• Zhongdian
• Zweibrücker Warmblut

🧬 Interpretation of genotypes LWO

預測後代