O que significa “Limpar”?
O animal não carrega a mutação. Não desenvolverá a doença e não vai passar adiante.
Cachorro Hipotireoidismo congênito com bócio em cão de água espanhol (CHG-SWD)
The DNA test for Congenital Hypothyroidism With Goiter (CHG) in Spanish Water Dogs is essential for responsible breeding. CHG is a hereditary thyroid disorder that can cause serious health issues in affected puppies. By using this genetic test, breeders can identify carriers and avoid producing affected offspring. Early detection through DNA testing helps maintain the health and vitality of the Spanish Water Dog breed. This test is simple, accurate, and crucial for preventing CHG-related complications. Ensure your Spanish Water Dog’s lineage is free from CHG by opting for this reliable DNA screening. Protect your dog’s future with the CHG DNA test today.
Abreviatura: CHG-SWD
Mutação analisada: TPO c.39_40insG
Herança: Autossômico Recessivo
Acrônimo
CHG-SWD
Frequência observada
Gravidade clínica
Classificação clínica
Doenças Endócrinas
Mutação analisada
TPO c.39_40insG
p.(R14Efs*184)
p.(R14Efs*184)
Modo de herança
Autossômico Recessivo
Resumo do teste:
The DNA test for Congenital Hypothyroidism With Goiter (CHG) in Spanish Water Dogs helps identify carriers and affected dogs. CHG is a genetic disorder causing thyroid gland dysfunction and goiter development. Early detection through testing allows breeders to make informed decisions to reduce the disease's prevalence. This improves the overall health and quality of the breed. Responsible breeding practices rely on such genetic screenings to prevent CHG in future generations.
Disponível no pacote: Basic
Este teste de DNA está incluído a partir do nosso pacote Basic - e também faz parte dos packs Basic, Standard, Advanced, Complete.
Ver pacotes de teste de DNA →Escolha o pack que melhor se adapta à sua estratégia de criação ou saúde dos seus animais.
Understanding Congenital Hypothyroidism With Goiter (CHG)
Congenital Hypothyroidism With Goiter (CHG) is a genetic condition that affects the thyroid gland's ability to produce hormones in affected dogs, particularly the Spanish Water Dog breed. This disorder leads to a deficiency in thyroid hormone levels, which are crucial for various bodily functions, including metabolism, growth, and development.
Symptoms of CHG
Dogs with CHG typically exhibit a range of symptoms that can affect their overall health and quality of life. Common signs include an enlarged thyroid gland, which may present as a noticeable swelling in the neck area, lethargy, poor coat quality, weight gain despite reduced appetite, and developmental delays in young dogs. These symptoms can vary in severity and may not appear until the dog is several weeks old.
Diagnosis of CHG
Diagnosis of Congenital Hypothyroidism With Goiter is primarily achieved through clinical evaluation and genetic testing. While physical symptoms can provide initial clues, confirming the diagnosis often requires a DNA test that identifies the specific genetic mutations associated with CHG. Early detection is essential for managing the condition effectively and improving the dog's quality of life.
Treatment Options
While there is no cure for CHG, the condition can be managed through lifelong treatment. The primary approach involves hormone replacement therapy, which typically includes administering synthetic thyroid hormones to restore normal hormone levels. This treatment helps alleviate many of the symptoms associated with the condition, allowing affected dogs to lead healthier and more active lives.
Prognosis for Affected Dogs
With appropriate treatment, dogs diagnosed with Congenital Hypothyroidism With Goiter can have a good prognosis. Regular monitoring and adjustments to medication may be necessary to ensure optimal hormone levels are maintained. However, affected dogs will require a lifelong commitment to management, including regular veterinary check-ups and adherence to prescribed treatments.
Conclusão
Congenital Hypothyroidism With Goiter is a serious genetic condition in dogs that requires early diagnosis and ongoing management. Understanding the symptoms, treatment options, and prognosis can help ensure that affected dogs receive the care they need to thrive. Owners of Spanish Water Dogs should consider genetic testing, especially if they have concerns about the health of their pets or the breed's predisposition to this condition.
Raça reconhecida para o teste: Hipotireoidismo congênito com bócio em cão de água espanhol (CHG-SWD)
- Spanish Water Dog
🧬 Interpretation of genotypes CHG-SWD
Genótipo
Status
🟡 N/N
Não portador - sem risco
🟡 N/CHG-SWD
Transportadora - Sem Risco
❌ CHG-SWD/CHG-SWD
Afetados - Em risco
FAQ: entendendo a interpretação
Um “transportador” é sério?
Não. O animal é geralmente saudável, mas pode transmitir a mutação ao seu descendência.
E se um animal for “afetado”?
Ele carrega duas cópias mutadas. Os sinais clínicos são esperados dependendo a doença. Não deveria ser criado.
Por que existem diferenças entre homem/mulher?
Algumas doenças estão ligadas ao sexo, pelo que a sua expressão varia dependendo do sexo do animal.
Prever descendência
N/N (nao-portador)
N/CHG-SWD (Operadora)
CHG-SWD/CHG-SWD (Afetado)
Perguntas frequentes sobre testes de DNA
O que este teste de DNA detecta?
This DNA test detects the mutation associated with Congenital Hypothyroidism With Goiter In Spanish Water Dog (CHG-SWD) in order to identify clear, carrier, or at-risk animals.
Por que testar um animal reprodutor?
Os testes de DNA ajudam os criadores a planejar acasalamentos mais seguros e a reduzir o risco de transmissão da mutação aos descendentes.
Qual é o modo de herança deste teste?
O modo de herança relatado para este teste é Autossômico Recessivo.
Qual mutação é analisada neste teste?
This test analyses the mutation TPO c.39_40insG.
Um animal portador é necessariamente afetado?
Não necessariamente. A interpretação depende do padrão de herança e do genótipo resultante.
Referências
Fyfe John C, Lynch Mary, Olsen Jayme, Lou?r Eric. A thyroid peroxidase (TPO) mutation in dogs reveals a canid-specific gene structure. Mamm Genome. 2013 Apr;24(3-4):127-33. doi: 10.1007/s00335-012-9442-y. Epub 2012 Dec 8.