O que significa “Limpar”?
O animal não carrega a mutação. Não desenvolverá a doença e não vai passar adiante.
Cavalo Castanha Variante E (extensão e)
The Chestnut Variant E (Extension e) DNA test in horses is essential for breeders aiming to understand coat color genetics. This test identifies the presence of the Extension gene variant responsible for red-based chestnut coloring. By analyzing the Extension e allele, breeders can predict offspring coat colors more accurately and make informed breeding decisions. The Chestnut Variant E test is quick, reliable, and widely used in equine genetic testing. Understanding this gene helps maintain breed standards and enhances the value of your horse. For optimal breeding outcomes, include the Extension e DNA test in your genetic panel today. Accurate genetic insights lead to healthier, more vibrant chestnut horses.
Abreviatura: extension e
Mutação analisada: MC1R c.248C/T
Herança: Autossômico Recessivo
Acrônimo
extension e
Frequência observada
Classificação clínica
Características relacionadas à pelagem
Mutação analisada
MC1R c.248C/T
p.(S83F)
p.(S83F)
Modo de herança
Autossômico Recessivo (Completo)
Nome alternativo:
E Locus
Resumo do teste:
The Chestnut Variant E (Extension e) in horses is a specific genetic marker that influences coat color. This variant affects the production of red pigment, resulting in chestnut or sorrel coat shades. Horses with the Extension e allele typically lack black pigment in their hair. DNA testing for this variant helps breeders predict and select desired coat colors. Understanding this gene is important for accurate breeding and color identification.
Disponível no pacote: Standard
Este teste de DNA está incluído a partir do nosso pacote Standard - e também faz parte dos packs Standard, Advanced, Complete.
Ver pacotes de teste de DNA →Escolha o pack que melhor se adapta à sua estratégia de criação ou saúde dos seus animais.
Introduction to Chestnut Variant E (Extension e)
The Chestnut Variant E, also known as the extension e allele, is a genetic trait found in horses that influences coat color. This variant is crucial for understanding the inheritance patterns of chestnut coloration in equines. The extension gene is responsible for the production of red pigments in a horse's coat, and its presence or absence determines whether a horse will exhibit chestnut, bay, or black coloration.
Genetic Basis of Chestnut Variant E
The extension locus (E) is located on equine chromosome 3 and plays a significant role in the pigmentation of a horse's coat. The dominant allele 'E' allows for the production of eumelanin, which is responsible for black and bay coats. Conversely, the recessive allele 'e' inhibits eumelanin production, resulting in a chestnut coat. Horses with two copies of the 'e' allele (ee) will display a chestnut coat color, while those carrying at least one 'E' allele will not.
Phenotypic Expression
While the presence of the extension e allele predominantly results in a chestnut coat color, various phenotypic expressions can occur based on other interacting genes. Factors such as sabino, roan, or varnish patterns may alter the appearance of the coat, even in horses that test positive for the extension e variant. The intensity of the chestnut coloration can also vary, with some horses exhibiting a deep, rich chestnut and others presenting a lighter, more golden hue.
Importance of Genetic Testing
DNA testing for the Chestnut Variant E is essential for breeders and owners who wish to understand and predict coat color inheritance in their horses. By knowing whether a horse carries the extension e allele, breeders can make informed decisions about pairings to achieve desired coat colors in future offspring. Additionally, genetic testing can help identify potential health implications associated with specific coat color traits, allowing for more responsible breeding practices.
Conclusão
The Chestnut Variant E (extension e) is a key genetic marker in the study of horse coat color inheritance. Understanding this variant not only aids in predicting coat color outcomes but also enhances the overall knowledge of equine genetics. As the field of equine genetics continues to evolve, DNA testing for the extension e allele remains a valuable tool for breeders and enthusiasts alike, contributing to the responsible breeding and management of horse populations.
Raça reconhecida para o teste: Castanha Variante E (extensão e)
- Arab
- Belgian Draft
- Clydesdale
- Freiberger
- Icelandic Horse
- Morgan
- Quarter Horse
- Shetland Pony
- Standardbred
- Thoroughbred
- Warmblood
- Welsh Pony
🧬 Interpretation of genotypes extension e
Genótipo
Status
🟡 E/E
Não portador – Sem efeito
🟡 E/e
Transportadora - Sem efeito
❌ e/e
Affected - Chestnut
FAQ: entendendo a interpretação
Um “transportador” é sério?
Não. O animal é geralmente saudável, mas pode transmitir a mutação ao seu descendência.
E se um animal for “afetado”?
Ele carrega duas cópias mutadas. Os sinais clínicos são esperados dependendo a doença. Não deveria ser criado.
Por que existem diferenças entre homem/mulher?
Algumas doenças estão ligadas ao sexo, pelo que a sua expressão varia dependendo do sexo do animal.
Prever descendência
E/E (nao-portador)
E/e (Operadora)
e/e (Afetado)
Perguntas frequentes sobre testes de DNA
O que este teste de DNA detecta?
This DNA test detects the mutation associated with Chestnut Variant E (extension e) in order to identify clear, carrier, or at-risk animals.
Por que testar um animal reprodutor?
Os testes de DNA ajudam os criadores a planejar acasalamentos mais seguros e a reduzir o risco de transmissão da mutação aos descendentes.
Qual é o modo de herança deste teste?
O modo de herança relatado para este teste é Autossômico Recessivo.
Qual mutação é analisada neste teste?
This test analyses the mutation MC1R c.248C/T.
Um animal portador é necessariamente afetado?
Não necessariamente. A interpretação depende do padrão de herança e do genótipo resultante.
Referências
Marklund L, Moller M J, Sandberg K, Andersson L. A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses. Mamm Genome. 1996 Dec;7(12):895-9. doi: 10.1007/s003359900264.