Cat Albinism C1 (C1)

Discover the fascinating world of genetics with the DNA test for Albinism C1 (C1) in cats. This specific test identifies the presence of the C1 gene, responsible for the striking white coat and blue eyes often seen in albino cats. Understanding your cat's genetic makeup can help you make informed breeding decisions and ensure the health of future generations. Early detection of albinism can also guide you in providing specialized care for your feline friend. By choosing the Albinism C1 DNA test, you contribute to responsible pet ownership and breed preservation. Explore the benefits of genetic testing today and unlock the secrets of your cat’s unique heritage!

Abbreviation : C1

Analysed mutation : TYR c.939del

Inheritance : Autosomal Recessive

Acronym

Observed frequency

Rare

Clinical classification

Coat-Related Traits

Analysed mutation

TYR c.939del
p.(S314Pfs*9)

Mode of inheritance

Autosomal Recessive

Alternate name:

C Locus

Test summary:

The DNA test for Albinism C1 (C1) in cats is a genetic screening that identifies the presence of the albinism gene. This test is crucial for breeders and pet owners who want to understand the potential coat color and health of their feline companions. Albinism in cats is characterized by a lack of pigment, resulting in a striking all-white appearance and light blue eyes. By conducting the C1 test, owners can make informed decisions about breeding and care, ensuring the well-being of their cats. Understanding this genetic trait helps promote responsible breeding practices and better health outcomes for future generations.

Available from the pack : Standard

This DNA test is included starting from our pack Standard — and is also part of the packs Standard, Advanced, Complete.

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Choose the pack that best fits your breeding or health strategy of your animals.

Understanding Albinism C1 in Cats

Albinism C1 is a genetic condition that affects the pigmentation of a cat's fur, skin, and eyes. This condition arises from a mutation in the gene responsible for producing melanin, the pigment that gives color to these features. Cats with Albinism C1 typically exhibit a lack of pigmentation, resulting in a white or very light coat, pink or light-colored skin, and blue eyes.

Genetics Behind Albinism C1

The genetic basis for Albinism C1 is linked to a specific mutation in the gene known as TYR (tyrosinase). This gene is crucial for the production of melanin, and its mutation leads to the inability to synthesize this pigment effectively. As a result, affected cats do not develop the usual coloration seen in their non-albino counterparts. Understanding the genetic foundation of Albinism C1 is essential for breeders and owners who want to be aware of the inheritance patterns and potential risks associated with the condition.

Clinical Implications of Albinism C1

Cats with Albinism C1 may face certain health challenges due to their lack of pigmentation. One of the most significant concerns is their increased sensitivity to sunlight, which can lead to sunburn and a higher risk of skin cancer. Additionally, the absence of melanin in the eyes may result in vision problems or increased susceptibility to eye-related issues, such as retinal damage. Therefore, it is crucial for owners of albino cats to take preventive measures to protect their pets from excessive sun exposure and monitor their overall health closely.

Management and Care for Albino Cats

Managing a cat with Albinism C1 involves providing a safe and supportive environment. Owners should ensure that their albino cats have limited exposure to direct sunlight by providing shaded areas and indoor spaces to retreat to during sunny days. Regular veterinary check-ups are also essential to monitor skin and eye health. Additionally, incorporating sunblock specifically designed for pets can help protect the skin of albino cats when they do go outside.

Conclusion

Albinism C1 is a unique genetic condition that presents both aesthetic and health-related challenges for affected cats. Understanding the implications of this condition, along with appropriate care and management strategies, can help ensure a happy and healthy life for albino cats. Awareness of the genetic factors and clinical implications can aid cat owners in making informed decisions and providing the best possible environment for their pets.

Breed recognized for the test : Albinism C1 (C1)

Abyssinian
Aegean
Alpine Lynx
Altai
American Bobtail
American Bobtail Longhair
American Bobtail Shorthair
American Burmese
American Curl
American Curl Longhair
American Curl Shorthair
American Fold Longhair
American Fold Shorthair
American Keuda
American Longhair
American Lynx
American Miniature Cat
American Polydactyl
American Ringtail
American Shorthair
American Straight Long Hair
American Straight Shorthair
American Wirehair
Anatoli
Aphrodite
Aphrodite Giant
Aphrodite's Giant Longhair
Aphrodite's Giant Shorthair
Arabian Mau
Asian
Asian Leopard Cat
Asian Longhair
Asian Semi-longhair
Asian Shorthair
Australian Bombay
Australian Mist
Aztec
Balinese
Bambino
Bambino Curl
BamBob
Bengal
Bengal Longhair
Birman
Bobcat
Bohemian Rex
Bombay
Bramble
Brazilian Shorthair
Bristol
British Ice Longhair
British Ice Shorthair
British Longhair
British Shorthair
Burmese
Burmese European
Burmese Longhair
Burmilla
Burmilla Longhair
Burmilla Shorthair
California Spangled
California Toyger
Californian Rex
Canadian Feral Cat
Canadian Sphynx
Caracal
Celtic
Celtic Shorthair
Ceylon
Chantilly-Tiffany
Chartreux
Chausie
Chinchilla Longhair
Chinese Harlequin
Chinese Li Hua
Chinese Tank Cat
Classicat
Colorpoint Shorthair
Companion Cat
Copper
Cornish Rex
Cornish Rex Longhair
Curly Tail Cat
Cymric
Cyprus
Desert Lynx
Deutsch Langhaar
Devon Rex
Domestic Longhair
Domestic medium-haired
Domestic Shorthair
Don Sphynx
Donskoy
Dossow
Dragon Li
Dwelf
Egyptian Mau
Elf
European
European Burmese
European Shorthair
Exotic
Exotic Shorthair
Experimental
Fishing Cat
Foldex
Foreign White
Foreign White Longhair
Foreign White Shorthair
Gao Taem
Genetta
Geoffroy's Cat
German Longhair
German Rex
Havana
Havana Brown
Hemingway Curl
Hibernian Lynx
Highland Fold
Highland Lynx
Highland Straight
Highlander
Highlander Longhair
Highlander Shorthair
Himalayan
House Cat Longhair
House Cat Shorthair
Household Pet
Household Pet Kitten
Household Pet Longhair
Household Pet Shorthair
Isle of Man Longhair
Isle of Man Shorthair
Jaguarette
Jaguarundi Curl
Japanese Bobtail
Japanese Bobtail Longhair
Japanese Bobtail Shorthair
Japanese domestic
Javanese
Jungala
Jungle Cat
Jungle Curl
Jungle Lynx
Junglebob
Kanaani
Karelian Bobtail
Karelian Bobtail Longhair
Khao Manee
Khaomanee
Kinkalow
Korat
Korean Bobtail
Korn Ja
Kurilian Bobtail
Kurilian Bobtail Longhair
Kurilian Bobtail Shorthair
Lambkin
LaPerm
LaPerm Longhair
LaPerm Shorthair
Lykoi
Maine Coon
Maine Coon Polydactyl
Manx
Manx Longhair
Manx Shorthair
Me-kong Bobtail
Meerkat
Mekong Bobtail
Minskin
Minuet
Minuet Longhair
Mixed Breed
Mohave Bob
Mojave Spotted
Mokave Jag Cat
Mountain Bob
Munchkin
Munchkin Longhair
Napoleon
Nebelung
Neva Masquerade
Niebelung
Non Recognized Hairless
Non Recognized Longhair
Non Recognized Shorthair
Norwegian Forest Cat
Ocicat
Ojos Azules
Oregon Rex (extinct)
Oriental
Oriental Bicolor
Oriental Longhair
Oriental Shorthair
Original Longhair
Owyhee Bob
Pantherette
Persian
Peterbald
Pharaoh
Pixiebob
Pixiebob Longhair
Puppykat
Raas
Ragamuffin
Ragdoll
Ruffle
Russian
Russian Black
Russian Blue
Russian Tabby
Russian White
Rusty Spotted Cat
Sacred Birman
Safari
Sam Sawet
Sashkin Rex
Savannah
Scottish Fold
Scottish Fold Longhair
Scottish Longhair
Scottish Shorthair
Scottish Straight
Scottish Straight Longhair
Selkirk Rex
Selkirk Rex Longhair
Selkirk Rex Shorthair
Selkirk Straight
Serengeti
Serrade Petit
Serval
Siamese
Siamese Longhair
Siberian
Singapura
Skookum
Snowbob
Snowshoe
Sokoke
Somali
Sphynx
Suffolk
Suphalak
Tennessee Bobtail
Tennessee Rex
Thai
Thai Blue Point
Thai Lilac
Thai Lilac Point
Tiffanie
Tigrette
Tonkinese
Tonkinese Longhair
Tonkinese Shorthair
Toybob
Toyger
Traditional Siamese
Transylvanian
Tundra
Turkish Angora
Turkish Van
Turkish Vankedisi
Ukrainian Levkoy
Unknown
Ural Rex
Ural Rex Longhair
Vienna Woods
Viverral
York Chocolate

Interpretation of genotypes Genotype Status Learn more about the interpretation of genotypes FAQ: understanding the interpretation of result What does “Clear” mean? The animal does not carry the mutation. It will not develop the disease and will not pass it on. Is a “Carrier” serious? No. The animal is generally healthy but can transmit the mutation to its offspring. What if an animal is “Affected”? It carries two mutated copies. Clinical signs are expected depending on the disease. It should not be bred. Why are there differences between male / female? Some diseases are sex-linked, so their expression varies depending on the animal’s sex. The animal has two normal copies of the gene. No risk of developing or transmitting the disease. Heterozygous carrier: one mutated copy. The animal is usually not clinically affected but can pass the mutation to offspring. Male carrier or affected depending on the inheritance mode. Males have only one X or Y chromosome. Heterozygous female carrier: one mutated copy. She can pass the mutation on and may sometimes show mild clinical signs depending on the condition. Two mutated copies of the gene. The animal is at risk of developing the associated condition.

🧬 Interpretation of genotypes C1

Genotype

Status

🟡 N/N

Non-carrier - No effect

🟡 N/c1

Carrier - No effect

❌ c1/c1

Affected - Albino

FAQ: understanding the interpretation

What does “Clear” mean?

The animal does not carry the mutation. It will not develop the disease and will not pass it on.

Is a “Carrier” serious?

No. The animal is generally healthy but can transmit the mutation to its offspring.

What if an animal is “Affected”?

It carries two mutated copies. Clinical signs are expected depending on the disease. It should not be bred.

Why are there differences between male / female?

Some diseases are sex-linked, so their expression varies depending on the animal’s sex.

Genotype Forecast for Offspring Mother Father Non-carrier Carrier Affected Favorable cross: majority Carrier risk is predominant. Majority affected Filter by mother's genotype Filter by father's genotype All Predict Offspring The animal has two normal copies of the gene. No risk of developing or transmitting the disease. Heterozygous carrier: one mutated copy. The animal is usually not clinically affected but can pass the mutation to offspring. Male carrier or affected depending on the inheritance mode. Males have only one X or Y chromosome. Heterozygous female carrier: one mutated copy. She can pass the mutation on and may sometimes show mild clinical signs depending on the condition. Two mutated copies of the gene. The animal is at risk of developing the associated condition.

Predict Offspring

Filter by mother's genotype Filter by father's genotype

N/N (Non-carrier)

N/c1 (Carrier)

c1/c1 (Affected)

DNA Test FAQ

What does this DNA test detect?

This DNA test detects the mutation associated with Albinism C1 (C1) in order to identify clear, carrier, or at-risk animals.

Why test a breeding animal?

DNA testing helps breeders plan safer matings and reduce the risk of transmitting the mutation to offspring.

What is the inheritance mode of this test?

The inheritance mode reported for this test is Autosomal Recessive.

Which mutation is analysed in this test?

This test analyses the mutation TYR c.939del.

Is a carrier animal necessarily affected?

Not necessarily. Interpretation depends on the inheritance pattern and the resulting genotype.

References

Imes D L, Geary L A, Grahn R A, Lyons L A. Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation. Anim Genet. 2006 Apr;37(2):175-8. doi: 10.1111/j.1365-2052.2005.01409.x.

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