Что означает «Очистить»?
Животное не является носителем мутации. Болезнь не разовьется и не передаст.
Primary Lens Luxation (PLL) is a hereditary eye condition affecting certain dog breeds, including the Border Collie and Jack Russell Terrier. A DNA test for PLL can help breeders make informed decisions, preventing the transmission of this debilitating condition. Early detection through genetic testing allows for proactive management of a dog's eye health, ensuring they live a happy, active life. By identifying carriers of the PLL gene, responsible breeding practices can be maintained, reducing the incidence of this disorder. Owners can safeguard their pets' vision and overall well-being with simple DNA testing. Don’t wait—invest in a PLL DNA test today to protect your furry friend from potential eye issues!
Primary Lens Luxation (PLL) is a genetic condition that affects certain dog breeds, leading to the displacement of the eye's lens. A DNA test can identify carriers of the PLL gene, helping breeders make informed decisions to reduce the risk of this hereditary issue in future litters. Early detection through genetic testing can help manage the condition more effectively if it arises. This test is particularly crucial for breeds like the Australian Terrier and the Basenji, where PLL is more prevalent. Responsible breeding practices can significantly improve the health and quality of life for affected dogs.
Этот ДНК-тест входит в комплект поставки, начиная с нашего пакета. Basic — а также входит в состав пакетов Basic, Standard, Advanced, Complete.
Посмотреть пакеты тестов ДНК →Primary Lens Luxation (PLL) is an inherited eye condition that leads to the displacement of the lens within the eye. This condition can result in severe complications, including glaucoma, cataracts, and even blindness if not treated promptly. PLL is caused by a genetic mutation that affects the zonules, the fibers that hold the lens in place. When these fibers become weak or absent, the lens can slip out of its normal position.
The genetic mutation responsible for PLL has been identified, and DNA testing has become a critical tool for diagnosing and managing this condition. By understanding the genetic factors at play, breeders and dog owners can make informed decisions to prevent the spread of PLL within affected populations. The DNA test identifies the presence of the specific mutation associated with the condition, allowing for early detection and intervention.
DNA testing for PLL is essential for responsible breeding practices. It helps to screen breeding animals for the genetic predisposition to the condition, thus reducing the risk of producing offspring that may inherit PLL. By identifying carriers of the mutation, breeders can make more informed choices about mating pairs, promoting healthier future generations.
The symptoms of Primary Lens Luxation can vary, but common signs include squinting, red eyes, and cloudiness of the lens. Affected dogs may also exhibit behavioral changes, such as bumping into objects or being hesitant to move around. Diagnosis typically involves a thorough ophthalmic examination by a veterinarian, who will assess the position of the lens and any associated complications.
Management of Primary Lens Luxation often involves a combination of surgical and medical interventions. In cases where the lens is dislocated, surgical removal may be necessary to alleviate pressure within the eye and prevent further complications. Additionally, medications may be prescribed to manage associated conditions like glaucoma. Regular follow-ups with a veterinarian are crucial to monitor the dog's eye health and adjust treatment plans as needed.
Primary Lens Luxation is a serious condition that can significantly impact a dog's quality of life. DNA testing provides an invaluable resource for breeders and pet owners to identify and manage this genetic disorder effectively. By understanding the genetic basis of PLL and taking proactive measures, we can work towards minimizing the incidence of this condition and ensuring healthier futures for our canine companions.
Животное не является носителем мутации. Болезнь не разовьется и не передаст.
Нет. В целом животное здорово, но может передать мутацию своему организму. потомство.
Он несет в себе две мутировавшие копии. Клинические признаки ожидаются в зависимости от болезнь. Его не следует разводить.
Некоторые заболевания связаны с полом, поэтому их выраженность варьируется в зависимости от пол животного.
This DNA test detects the mutation associated with Primary Lens Luxation (PLL) in order to identify clear, carrier, or at-risk animals.
Тестирование ДНК помогает заводчикам планировать более безопасные спаривания и снизить риск передачи мутации потомству.
Тип наследования, указанный для этого теста, — аутосомно-доминантный.
This test analyses the mutation ADAMTS17 c.1473+1G>A.
Не обязательно. Интерпретация зависит от характера наследования и полученного генотипа.
Farias Fabiana H G, Johnson Gary S, Taylor Jeremy F, Giuliano Elizabeth, Katz Martin L, Sanders Douglas N, Schnabel Robert D, McKay Stephanie D, Khan Shahnawaz, Gharahkhani Puya, O'Leary Caroline A, Pettitt Louise, Forman Oliver P, Boursnell Mike, McLaughlin Bryan, Ahonen Saija, Lohi Hannes, HernandezMerino Elena, Gould David J, Sargan David R, Mellersh Cathryn. An ADAMTS17 splice donor site mutation in dogs with primary lens luxation. Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4716-21. doi: 10.1167/iovs.09-5142. Epub 2010 Apr 7.
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